Heptanal, oligomeric reaction products with aniline

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 17 June 2016 to 13 September 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Study was conducted in accordance with EU, OECD, and US EPA test guidelines in an accredited GLP laboratory.

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Version / remarks:

March 23, 2006

Deviations:

not specified

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Version / remarks:

August 24, 2009.

Deviations:

not specified

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7950 (Vapor Pressure)

Version / remarks:

August 1996

Deviations:

not specified

GLP compliance:

yes

Type of method:

effusion method: isothermal thermogravimetry

Specific details on test material used for the study:

Purity/composition correction factor: No correction factor required
Test item handling: No specific handling conditions required

Key result

Temp.:

20 °C

Vapour pressure:

>= 0.009 - <= 0.36 Pa

Key result

Temp.:

25 °C

Vapour pressure:

>= 0.45 - <= 0.49 Pa

The plot of the log PT of the test item as function of the reciprocal temperatures conducted from the results of the first two experiments had a coefficient of correlation (r) < 0.99.Therefore, a third experiment was performed. Evaluating each measurement separately, the coefficients of correlation (r) were > 0.99. Combining two of the three or all three curves, however, coefficients of correlation (r) were < 0.99. Therefore, the three measurements were evaluated separately and the vapour pressure of the test item was determined as a range of three individual experiments.

 

Results of the isothermal TGA analysis

Experiment	Temperature[°C]	Weight loss [µg/min]	νT[g/cm2/h]	log νT	log PT	PT[Pa]
1	70	3.159	3.77´10-4	-3.42	0.64	4.4
	80	6.094	7.27´10-4	-3.14	0.97	9.3
	90	9.431	1.13´10-3	-2.95	1.19	15
2	70	3.970	4.74´10-4	-3.32	0.76	5.7
	80	6.994	8.35´10-4	-3.08	1.04	11
	90	10.91	1.30´10-3	-2.89	1.26	18
3	70	3.958	4.72´10-4	-3.33	0.76	5.7
	80	6.471	7.72´10-4	-3.11	1.00	10
	90	8.727	1.04´10-3	-2.98	1.15	14

 

Vapour pressure of the test item (Experiment 1)

Temperature[°C]	log PT	PT[Pa]	PT [mm Hg]
20	-1.02	9.5´10-2	7.1´10-4
25	-0.83	0.15	1.1´10-3

 

Vapour pressure of the test item (Experiment 2)

Temperature[°C]	log PT	PT[Pa]	PT [mm Hg]
20	-0.79	0.16	1.2´10-3
25	-0.61	0.25	1.8´10-3

 

Vapour pressure of the test item (Experiment 3)

Temperature[°C]	log PT	PT[Pa]	PT [mm Hg]
20	-0.45	0.36	2.7´10-3
25	-0.31	0.49	3.7´10-3

Conclusions:

The isothermal TGA effusion method was applied for the determination of the vapour pressure of Hepteen Base®.

The vapour pressure of the test item at 20°C (293K) and 25°C (298K) was:
20°C; 9.5 x 10-2 to 0.36 Pa =7.1 x 10-4 to 2.7 x 10-3 mm Hg
25°C; 0.15 to 0.49 Pa = 1.1 x 10-3 – 3.7x 10-3 mm Hg

Executive summary:

A study to determine the vapour pressure of Hepteen Base® was conducted using isothermal TGA effusion in accordance with the following test guidelines in a GLP accredited laboratory.

European Community (EC), EC no. 761/2009, Part A: Methods for the Determination of Physico-Chemical Properties, Guideline A.4: “Vapour Pressure", Official Journal of the European Union no. L220, August 24,2009.

Organization for Economic Co-operation and Development (OECD), OECD Guidelines for the Testing of Chemicals no.104: "Vapour Pressure", March 23, 2006.

United States Environmental Protection Agency (EPA), Product Properties Test Guidelines no. OPPTS 830.7950: "Vapour pressure", August 1996.

 

The vapour pressure of the test item at 20°C (293K) and 25°C (298K) was:

20°C; 9.5 x 10-2 to 0.36 Pa =7.1 x 10-4 to 2.7 x 10-3 mm Hg

25°C; 0.15 to 0.49 Pa = 1.1 x 10-3 – 3.7x 10-3 mm Hg

Description of key information

The vapour pressure of the test item at 20°C (293K) and 25°C (298K) was: 20°C; 9.5 x 10-2 to 0.36 Pa =7.1 x 10-4 to 2.7 x 10-3 mm Hg 25°C; 0.15 to 0.49 Pa = 1.1 x 10-3 – 3.7x 10-3 mm Hg

Key value for chemical safety assessment

Vapour pressure:

0.49 Pa

at the temperature of:

25 °C

Additional information

A study to determine the vapour pressure of Hepteen Base® was conducted using isothermal TGA effusion in accordance with the following test guidelines in a GLP accredited laboratory.

 European Community (EC), EC no. 761/2009, Part A: Methods for the Determination of Physico-Chemical Properties, Guideline A.4: “Vapour Pressure", Official Journal of the European Union no. L220, August 24,2009.

Organization for Economic Co-operation and Development (OECD), OECD Guidelines for the Testing of Chemicals no.104: "Vapour Pressure", March 23,2006.

United States Environmental Protection Agency (EPA), Product Properties Test Guidelines no. OPPTS 830.7950: "Vapour pressure", August 1996.