Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

acute toxicity: inhalation
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because exposure of humans via inhalation is not likely taking into account the vapour pressure of the substance and/or the possibility of exposure to aerosols, particles or droplets of an inhalable size
Justification for type of information:
In accordance with Annex VIII of REACH, Column 2, testing via inhalation is only appropriate if exposure of humans is likely. Vapour pressure of 2-Propenoic acid, 2-methyl-, tetracosyl ester(branched) was investigated during a study performed in accordance with ASTM D2879 - 97 Standard Test Method for Vapour Pressure-Temperature Relationship and Initial Decomposition Temperature of Liquids by Isoteniscope, which concluded that the substance has a vapour pressure below 100 Pa. In addition formation of aerosols during the use of the substance is unlikely. It is therefore concluded that exposure to 2-Propenoic acid, 2-methyl-, tetracosyl ester(branched) is unlikely and that it is not appropriate to investigate this route exposure.

Data source

Materials and methods

Results and discussion

Clinical signs:

Applicant's summary and conclusion