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EC number: 945-713-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Toxicity to terrestrial plants
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to terrestrial plants: long-term
- Data waiving:
- exposure considerations
- Justification for data waiving:
- the study does not need to be conducted because direct and indirect exposure of the soil compartment is unlikely
- Justification for type of information:
- JUSTIFICATION FOR DATA WAIVING
In accordance with column 2 of REACH Annex IX, the study does not need to be conducted since direct and indirect exposure of the soil compartments is unlikely. - Endpoint:
- toxicity to terrestrial plants: short-term
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- significant methodological deficiencies
- Remarks:
- A reference substance (toxic standard) was not included in the experimental design. Neither description of the test method followed nor data on GLP.
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- - Principle of test: Study on inhibition of germination, i.e. seedling emergence, of lettuce fruit (Lactuca saliva L. cv. Great Lakes).
- Short description of test conditions: see below
- Parameters analysed / observed: 3 day-EC50 - GLP compliance:
- not specified
- Specific details on test material used for the study:
- Test compound was used as received from the manufacturer without further purification.
- Vehicle:
- no
- Details on preparation and application of test substrate:
- - Method of application: Agar (0.5%) was used as a germination substrate and contained the test compounds in solution
- Controls: germination substrate only with water - Species:
- Lactuca sativa
- Plant group:
- Dicotyledonae (dicots)
- Details on test organisms:
- - Common name: lettuce fruit
- Plant family: asteraceae
- Variety: Great Lakes - Test type:
- seedling emergence toxicity test
- Study type:
- semi-field study
- Substrate type:
- artificial soil
- Remarks:
- agar (0.5%)
- Limit test:
- yes
- Total exposure duration:
- 3 d
- Test temperature:
- 30 ºC
- Details on test conditions:
- Ambient light
- Reference substance (positive control):
- no
- Key result
- Species:
- Lactuca sativa
- Duration:
- 3 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 5 other: mM
- Nominal / measured:
- estimated
- Conc. based on:
- test mat.
- Basis for effect:
- germination
- Remarks on result:
- other: effect limited by test item solubility in water
- Validity criteria fulfilled:
- no
- Conclusions:
- The 3 day-EC50 based on inhibition of germination for the test item on lettuce fruit (Lactuca saliva L. cv. Great Lakes) was estimated to be higher than 5 mM (681.2 mg/L).
- Executive summary:
A Study on inhibition of germination of lettuce fruit (Lactuca saliva L. cv. Great Lakes) was performed on alicyclic compounds including some monoterpenes and in particular on L-camphene. Agar (0.5%) was used as a germination substrate and contained the test compound in solution. The test was carried out for 3 days at 30 °C in ambient light. A negative control based on the same substrate only with water was used. The 3 day-EC50 for the test item was estimated to be higher than 5 mM (681.2 mg/L).
- Endpoint:
- toxicity to terrestrial plants: short-term
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- significant methodological deficiencies
- Remarks:
- A reference substance (toxic standard) was not included in the experimental design. Neither description of the test method followed nor data on GLP.
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- - Principle of test: Study on inhibition of germination, i.e. seedling emergence, of lettuce fruit (Lactuca saliva L. cv. Great Lakes).
- Short description of test conditions: see below
- Parameters analysed / observed: 3 day-EC50 - GLP compliance:
- not specified
- Specific details on test material used for the study:
- Test compound was used as received from the manufacturer without further purification.
- Vehicle:
- no
- Details on preparation and application of test substrate:
- - Method of application: Agar (0.5%) was used as a germination substrate and contained the test compounds in solution
- Controls: germination substrate only with water - Species:
- Lactuca sativa
- Plant group:
- Dicotyledonae (dicots)
- Details on test organisms:
- - Common name: lettuce fruit
- Plant family: asteraceae
- Variety: Great Lakes - Test type:
- seedling emergence toxicity test
- Study type:
- semi-field study
- Substrate type:
- artificial soil
- Remarks:
- agar (0.5%)
- Limit test:
- yes
- Total exposure duration:
- 3 d
- Test temperature:
- 30 ºC
- Details on test conditions:
- Ambient light
- Reference substance (positive control):
- no
- Key result
- Species:
- Lactuca sativa
- Duration:
- 3 d
- Dose descriptor:
- EC50
- Effect conc.:
- 1.3 other: mM
- Nominal / measured:
- estimated
- Conc. based on:
- test mat.
- Basis for effect:
- germination
- Remarks on result:
- other: confidence limit: ±0.5mM
- Validity criteria fulfilled:
- no
- Conclusions:
- The 3 day-EC50 based on inhibition of germination for the test item on lettuce fruit (Lactuca saliva L. cv. Great Lakes) was estimated to be 1.3±0.5mM (177±68 mg/L).
- Executive summary:
A Study on inhibition of germination of lettuce fruit (Lactuca saliva L. cv. Great Lakes) was performed on alicyclic compounds including some monoterpenes and in particular on alpha pinene. Agar (0.5%) was used as a germination substrate and contained the test compound in solution. The test was carried out for 3 days at 30 °C in ambient light. A negative control based on the same substrate only with water was used. The 3 day-EC50 for the test item was estimated to be 1.3±0.5mM (177±68 mg/L).
- Endpoint:
- toxicity to terrestrial plants: short-term
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Justification for type of information:
- REPORTING FORMAT FOR THE ANALOGUE APPROACH
The analogue substance alpha pinene which shares the same functional groups with the main components of the multi-constituent substance reaction mass of fenchene and laevo camphene and dextro camphene and laevo alpha pinene also has comparable values for the relevant molecular properties.
See attached the reporting format. - Reason / purpose for cross-reference:
- read-across source
- Key result
- Species:
- Lactuca sativa
- Duration:
- 3 d
- Dose descriptor:
- EC50
- Effect conc.:
- 1.3 other: mM
- Nominal / measured:
- estimated
- Conc. based on:
- other: Read-across from an analogue
- Basis for effect:
- germination
- Remarks on result:
- other: read-across from an analogue for which EC50 (3d) = 1.3 mM (confidence limit: ±0.5mM)
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- Based on the read-across approach from the analogue alpha pinene, the 3 day-EC50 for the reaction mass based on inhibition of germination on lettuce fruit (Lactuca saliva L. cv. Great Lakes) was estimated to be 1.3±0.5mM (177±68 mg/L).
- Executive summary:
A Study on inhibition of germination of lettuce fruit (Lactuca saliva L. cv. Great Lakes) was performed on alicyclic compounds including some monoterpenes and in particular on alpha pinene. Agar (0.5%) was used as a germination substrate and contained the test compound in solution. The test was carried out for 3 days at 30 °C in ambient light. A negative control based on the same substrate only with water was used. The 3 day-EC50 for the test item was estimated to be 1.3±0.5mM (177±68 mg/L). Based on these results, the read-across approach was applied and the 3 day-EC50 for the reaction mass was estimated to be 1.3±0.5mM (177±68 mg/L).
- Endpoint:
- toxicity to terrestrial plants: short-term
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Justification for type of information:
- REPORTING FORMAT FOR THE ANALOGUE APPROACH
The analogue substance L-camphene which shares the same functional groups with the main components of the multi-constituent substance reaction mass of fenchene and laevo camphene and dextro camphene and laevo alpha pinene also has comparable values for the relevant molecular properties.
See attached the reporting format. - Reason / purpose for cross-reference:
- read-across source
- Key result
- Species:
- Lactuca sativa
- Duration:
- 3 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 5 other: mM
- Nominal / measured:
- estimated
- Conc. based on:
- other: Read-across from an analogue
- Basis for effect:
- germination
- Remarks on result:
- other: read-across from an analogue for which EC50 (3 d) > 5 mM
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- Based on the read-across approach from the analogue L-camphene, the 3 day-EC50 for the reaction mass based on inhibition of germination on lettuce fruit (Lactuca saliva L. cv. Great Lakes) was estimated to be higher than 5 mM (681.2 mg/L).
- Executive summary:
A Study on inhibition of germination of lettuce fruit (Lactuca saliva L. cv. Great Lakes) was performed on alicyclic compounds including some monoterpenes and in particular on L-camphene. Agar (0.5%) was used as a germination substrate and contained the test compound in solution. The test was carried out for 3 days at 30 °C in ambient light. A negative control based on the same substrate only with water was used. The 3 day-EC50 for the test item was estimated to be higher than 5 mM (681.2 mg/L). Based on these results, the read-across approach was applied and the 3 day-EC50 for the reaction mass was estimated to be higher than 5 mM (681.2 mg/L).
Referenceopen allclose all
Description of key information
Data waiving (exposure considerations): According to the column 2 of REACH Annex IX, the study does not be conducted since direct and indirect exposure of the soil compartment is unlikely.
Supporting study: Read-across approach. L-camphene: Based on the read-across approach from the analogue L-camphene, the 3 day-EC50 for the reaction mass based on inhibition of germination on lettuce fruit (Lactuca saliva L. cv. Great Lakes) was estimated to be higher than 5 mM (681.2 mg/L).
Supporting study: Read-across approach. alpha pinene: Based on the read-across approach from the analogue alpha pinene, the 3 day-EC50 for the reaction mass based on inhibition of germination on lettuce fruit (Lactuca saliva L. cv. Great Lakes) was estimated to be 1.3±0.5mM (177±68 mg/L).
Key value for chemical safety assessment
Additional information
Data waiving (exposure considerations): According to the column 2 of REACH Annex IX, the study does not be conducted since direct and indirect exposure of the soil compartment is unlikely.
Supporting study: Read-across approach. L-camphene: A Study on inhibition of germination of lettuce fruit (Lactuca saliva L. cv. Great Lakes) was performed on alicyclic compounds including some monoterpenes and in particular on L-camphene. Agar (0.5%) was used as a germination substrate and contained the test compound in solution. The test was carried out for 3 days at 30 °C in ambient light. A negative control based on the same substrate only with water was used. The 3 day-EC50 for the test item was estimated to be higher than 5 mM (681.2 mg/L). Based on these results, the read-across approach was applied and the 3 day-EC50 for the reaction mass was estimated to be higher than 5 mM (681.2 mg/L).
Supporting study: Read-across approach. alpha pinene: A Study on inhibition of germination of lettuce fruit (Lactuca saliva L. cv. Great Lakes) was performed on alicyclic compounds including some monoterpenes and in particular on alpha pinene. Agar (0.5%) was used as a germination substrate and contained the test compound in solution. The test was carried out for 3 days at 30 °C in ambient light. A negative control based on the same substrate only with water was used. The 3 day-EC50 for the test item was estimated to be 1.3±0.5mM (177±68 mg/L). Based on these results, the read-across approach was applied and the 3 day-EC50 for the reaction mass was estimated to be 1.3±0.5mM (177±68 mg/L).
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