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Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Experimental starting date: 07 August 2017 Experimental completion date: 21 August 2017
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: vapour pressure balance

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(2H-benzotriazol-2-yl)-4-tert-butylphenol
EC Number:
221-574-0
EC Name:
2-(2H-benzotriazol-2-yl)-4-tert-butylphenol
Cas Number:
3147-76-0
Molecular formula:
C16H17N3O
IUPAC Name:
2-(5-tert-Butyl-2-hydroxyphenyl)benzotriazole
Test material form:
solid: particulate/powder
Specific details on test material used for the study:
Batch: 02002IX3
Purity: 99.9%
Expiry date: 25 August 2017
Storage conditions: Room temperature in the dark

Results and discussion

Vapour pressure
Key result
Temp.:
25 °C
Vapour pressure:
0.003 Pa

Any other information on results incl. tables

The test item did not change in appearance under the conditions used in the determination.

No statistical analyses were performed because the balance readings were too low and variable for a line of best fit to have any meaning. Instead it was considered more appropriate to impose a regression slope on a chosen data point to provide an estimate of the maximum value for the vapor pressure at 25 ºC.

Run 10 was chosen because the sample had been under vacuum for the longest period prior to this run and so degassing would have been the most complete. The reading at 76 ºC (349.15 K) was chosen because this is the data point which gives the highest estimated vapor pressure at any given temperature when a slope of –1500 K is imposed upon it.

The value of –1500 K is an in-house value and is the shallowest slope observed whilst determining the vapor pressure on a wide range of samples using the vapor pressure balance method. Extrapolation to 25 ºC gave a vapor pressure of 2.81 x 10-3 Pa which has been taken as a maximum for this material.

Applicant's summary and conclusion

Conclusions:
The vapor pressure of the test item has been determined to be less than 2.9 x 10^-3 Pa at 25 ºC.
Executive summary:

The vapor pressure of the test item (EC# 221-574-0) has been determined to be less than 2.9 x 10-3 Pa at 25 °C, using the vapor pressure balance method, designed to be compatible with Method A.4 Vapour Pressure of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 104 of the OECD Guidelines for Testing of Chemicals, 23 March 2006.