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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
15 Mar 17 - 28 Feb 18
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient - HPLC Method)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC method

Test material

1
Chemical structure
Reference substance name:
2-(2H-benzotriazol-2-yl)-4-tert-butylphenol
EC Number:
221-574-0
EC Name:
2-(2H-benzotriazol-2-yl)-4-tert-butylphenol
Cas Number:
3147-76-0
Molecular formula:
C16H17N3O
IUPAC Name:
2-(2H-1,2,3-benzotriazol-2-yl)-4-tert-butylphenol
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No. of test material: 02002IX3
- Expiration date of the lot/batch: 28 February 2018
- Purity: 99.9 %
- Physical appearance: White powder.

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: Room temperature in the dark

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
ca. 6.15
Temp.:
25 °C
pH:
ca. 7.2

Applicant's summary and conclusion

Conclusions:
The partition coefficient of the test item has been determined to be log10 Pow 6.15.