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Environmental fate & pathways

Endpoint summary

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Indirect exposure of the aquatic compartment is likely.  Data are available for the log Pow of the main components of 1,3-Propanediol, 2,2-bis(hydroxymethyl)-, allyl ether at 25°C, with the two main components' log Pow values ranging from 1.5 to 3.0 and the third component showing a log Pow value of 4.8, thus the bioaccumulation potential of 1,3-Propanediol, 2,2-bis(hydroxymethyl)-, allyl ether is considered uncertain based on log Pow alone. The bioaccumulation potential of 1,3-Propanediol, 2,2-bis(hydroxymethyl)-, allyl ether was therefore estimated in the VEGA software (version 1.2.3) using the CAESAR (version 2.1.14) and NN/Read-Across (version 1.1.0) QSAR models, however these predictions were shown to be unreliable. It is therefore not possible to reliably assess the bioaccumulation potential of the substance according to Annex XI of the REACH regulation on the basis of the available information.  Therefore in accordance with Column 2 of Annex IX of the REACH regulation a fish bioaccumulation study is required to assess the bioacculation potential of the substance.  As such, a testing proposal is submitted for the performance of an OECD 305 Guideline study to reliably assess the bioaccumulation potential of the substance.

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