Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 111 (Hydrolysis as a Function of pH)
Deviations:
yes
Remarks:
see free text
Principles of method if other than guideline:
Additional pH value: pH 1.2 @ 40°C
Additional samples form all pH t= 30 min after mixing Butylchlorotin dihydroxide with buffer solutions
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Butylchlorodihydroxystannane
EC Number:
236-406-1
EC Name:
Butylchlorodihydroxystannane
Cas Number:
13355-96-9
Molecular formula:
C4H11ClO2Sn
IUPAC Name:
butylchlorodihydroxystannane
Test material form:
solid: granular
Radiolabelling:
no

Study design

Analytical monitoring:
yes
Duration of testopen allclose all
Duration:
30 min
pH:
1.2
Temp.:
40 °C
Initial conc. measured:
0.1 mol/L
Duration:
4 h
pH:
1.2
Temp.:
40 °C
Initial conc. measured:
0.1 mol/L
Duration:
30 min
pH:
4
Temp.:
50 °C
Initial conc. measured:
0.1 mol/L
Duration:
5 d
pH:
4
Temp.:
50 °C
Initial conc. measured:
0.1 mol/L
Duration:
30 min
pH:
7
Temp.:
50 °C
Initial conc. measured:
0.1 mol/L
Duration:
5 d
pH:
7
Temp.:
50 °C
Initial conc. measured:
0.1 mol/L
Duration:
30 min
pH:
9
Temp.:
50 °C
Initial conc. measured:
0.1 mmol/L
Duration:
5 d
pH:
9
Temp.:
50 °C
Initial conc. measured:
0.1 mol/L
Positive controls:
no
Negative controls:
no
Statistical methods:
not relevant

Results and discussion

Preliminary study:
yes, 30 min
Transformation products:
yes
Remarks:
for all pH
Identity of transformation products
No.:
#1
Reference
Reference substance name:
Unnamed
IUPAC name:
butyl(oxo)stannanol
Inventory number:
InventoryMultipleMappingImpl [inventoryEntryValue=EC 218-880-1]
CAS number:
2273-43-0
Identity:
1-Butanestannonic acid
Identity:
Stannane, butylhydroxyoxo-
Identity:
butyl(hydroxy)stannanone
Molecular formula:
C4H10O2Sn
Molecular weight:
208.83
SMILES notation:
CCCC[Sn](=O)O
InChl:
InChI=1/C4H9.H2O.O.Sn/c1-3-4-2;;;/h1,3-4H2,2H3;1H2;;/q;;;+1/p-1/rC4H10O2Sn/c1-2-3-4-7(5)6/h5H,2-4H2,1H3
Details on hydrolysis and appearance of transformation product(s):
the substance hydrolysis cobletly in butylhydroxystannae
Total recovery of test substance (in %)
Remarks on result:
not determinable
Remarks:
very low solubility
Dissipation DT50 of parent compoundopen allclose all
Key result
pH:
1.2
Temp.:
40 °C
DT50:
< 30 min
Type:
not specified
Remarks on result:
not determinable because of methodological limitations
Remarks:
no accurate determination of t(1/2) possible based on time of analysis
Key result
pH:
4
Temp.:
50 °C
DT50:
< 30 min
Type:
not specified
Remarks on result:
not determinable because of methodological limitations
Remarks:
no accurate determination of t(1/2) possible based on time of analysis
Key result
pH:
7
Temp.:
50 °C
DT50:
< 30 min
Type:
not specified
Remarks on result:
not determinable because of methodological limitations
Remarks:
no accurate determination of t(1/2) possible based on time of analysis
Key result
pH:
9
Temp.:
50 °C
DT50:
< 90 min
Type:
not specified
Remarks on result:
not determinable because of methodological limitations
Remarks:
no accurate determination of t(1/2) possible based on time of analysis
Details on results:
the samples taken show after 4h respective 5d no fruther changes

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The substance hydrolyses at contact with water at all tested pH below 30 minutes in momobutylhydroxystannane (MBTO, CAS+ 2273-43-0)