C16-18 (evennumbered, C18 unsaturated) alkyl bis(2-hydroxyethyl) amine oxide

Acute Toxicity: inhalation

Administrative data

Endpoint:

acute toxicity: inhalation

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because exposure of humans via inhalation is not likely taking into account the vapour pressure of the substance and/or the possibility of exposure to aerosols, particles or droplets of an inhalable size

Justification for type of information:

The test substance has a low vapour pressure 0.00073 pa at 20°C and is manufactured and sold as a 50% paste with 25% diethylene glycol and 25% water. Due to the combination of the low acute oral toxicity, the low vapour pressure and the lack of potential for inhalation exposure due to its physical form as a paste it is considered not justified from an animal well-fare perspective to perform any additional acute dose toxicity studies. Therefore acute inhalation testing has not been performed, the study is waived as not scientifically justified.