Registration Dossier
Registration Dossier
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EC number: 457-660-1 | CAS number: 104797-47-9
Endpoint summary
Administrative data
Description of key information
The LC50,96h for Brachydanio rerio is higher than 100 mg/L, based on the loading rate. The EC50,48h for daphnids, based on the loading rate, is higher than 100 mg/L. The EC50 for algae was based on a water accommodated fraction (WAF) after loading 111 mg test substance / L, and using the dissolved part. The ErC50 is between 1/2 WAF and WAF. ¼ WAF did not reduce the growth rate. These LC50/EC50 are higher than the water solubility of the substance of ca. 0.08 mg/L and are not directly suitable for a classification, but they demonstrates that the mixture, i.e. the pure substance and its impurities, as far as they are soluble at ca. 100 mg mixture/L, is not toxic or of low aquatic toxicity.
The impurity benzothiazole-2-thiol (typically 1.2 % in T15-AE) is classified in CLP as Aquatic Acute 1 H400 and Aquatic Chronic 1 H410. The LC50/EC50s of Benzothiazole-2-thiol are 0.73 mg/L (fish), 0.71 mg/L (daphnids) and 0.50 mg/L (algae). The water solubility is 118 mg/L at 25 °C and the substance is not readily biodegradable.
Applying the additivity formula of section 4.1.3.5.2. in CLP, the following LC50/EC50s of the mixture (= T15-AE) are obtained: 61 mg/L (fish), 59 mg/L (daphnids) and 46 mg/L (algae).
Additional information
The substance did not effect the respiration of activated sludge microorganisms up to at least a concentration of 300 mg loading rate/L.
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