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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Classification & Labelling & PBT assessment

PBT assessment

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Administrative data

PBT assessment: overall result

Pentyl salicylate
Type of composition:
legal entity composition of the substance
State / form:
Reference substance:
Pentyl salicylate
PBT status:
the substance is not PBT / vPvB


The substance is readily biodegradable. Hence, the substance is not considered to be persistent.


For the PBT and vPvB assessment a screening criterion has been established, which is log Kow greater than 4.5. Amyl salicylate has a measured log Kow of 4.4 to 4.5, which is just below this screening criterion. For organic substances with a log Kow below 4.5 it is assumed that the affinity for the lipids of an organism is insufficient to exceed the B criterion, i.e. a BCF value of 2000 L/kg. Since there is evidence that amyl salicylate is metabolised in fish, the aquatic BCF of amyl salicylate is expected to be lower than that predicted from log Kow. Indeed, the estimated BCF value for Amyl Salicyate based on read-across from analogue data is in the range of 380 to 570 L/kg. This is well below the B definitive criterion of BCF > 2000 L/kg. Therefore amyl salicylate does not fulfil the B-criteria.



E(L)C50 values for fish, daphnia and algae are > 0.1mg/L. Furthermore, there is no evidence of chronic toxicity, STOT RE or CMR effects.