Registration Dossier

Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Referenceopen allclose all

Endpoint:
solubility in organic solvents / fat solubility
Remarks:
ethanol, toluene
Type of information:
experimental study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
other: OECD Guideline 105: Water solubility (column elution method - flask method)
Qualifier:
according to guideline
Guideline:
other: EU MEthod A.6: Water solubility
GLP compliance:
yes (incl. QA statement)
Remarks:
Staatstoezicht op de Volkgezondheid, Verinaire Hoofdinspectie, The Netherlands
Medium:
ethanol
Solubility:
> 784 g/L
Remarks on result:
other: sodium 2-biphenylate tetrahydrate
Remarks:
preliminary test, no undissolved test substance observed at ambient temperature
Medium:
toluene
Solubility:
0.45 g/L
Temp.:
20 °C
Remarks on result:
other: sodium 2-biphenylate tetrahydrate
Endpoint:
solubility in organic solvents / fat solubility
Remarks:
n-octanol
Type of information:
experimental study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
other: OECD Guideline 105: Water solubility (column elution method - flask method)
Qualifier:
according to guideline
Guideline:
other: EU Method A.6: Water solubility
GLP compliance:
yes (incl. QA statement)
Remarks:
Staatstoezicht op de Volksgezondheid, Veterinaire Hoofdinspectie, Rijswijk, The Netherlands
Medium:
n-octanol
Solubility:
> 275 g/kg solvent
Remarks on result:
other: sodium 2-biphenylate tetrahydrate
Remarks:
at room temperature

Description of key information

275 g/kg in n-octanol at room temperature

> 784 g/L in ethanol at ambient temperature

0.45 g/L in toluene at 20 °C

(given as sodium 2-biphenylate tetrahydrate, OECD Guideline 105, flask method)

Key value for chemical safety assessment

Additional information