Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2014

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
not specified
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
α-acetyl-γ-butyrolactone
EC Number:
208-235-2
EC Name:
α-acetyl-γ-butyrolactone
Cas Number:
517-23-7
Molecular formula:
C6H8O3
IUPAC Name:
α-acetyl-γ-butyrolactone

Results and discussion

Partition coefficientopen allclose all
Type:
Pow
Partition coefficient:
0.37
Temp.:
22 °C
pH:
5.8
Key result
Type:
log Pow
Partition coefficient:
-0.43
Temp.:
22 °C
pH:
5.8

Applicant's summary and conclusion

Conclusions:
The partition coefficient of the test substance at 22°C was determined to be:
POW: 0.37
log POW: - 0.43