Registration Dossier

Diss Factsheets

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Endpoint:
partition coefficient
Type of information:
not specified
Adequacy of study:
weight of evidence
Study period:
2018
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
review article or handbook
Title:
Exploring QSAR:  Hydrophobic, Electronic, and Steric Constants
Author:
Hansch, C., A. Leo, and D. Hoekman
Year:
1995
Bibliographic source:
American Chemical Society, Washington, DC. 1995. Xix + 348 pp. 22 × 28.5 cm.

Materials and methods

Principles of method if other than guideline:
Data compilation and evaluation of methods
GLP compliance:
not specified
Other quality assurance:
other: Professional experience of the Chemists, Hansch and coworkers are primary source for high quality log Kow data
Remarks:
Hansch is global leading expert on Kow
Type of method:
other: not specified but up to date
Remarks:
No doubt about validy
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
1,3-dichloropropane
EC Number:
205-531-3
EC Name:
1,3-dichloropropane
Cas Number:
142-28-9
Molecular formula:
C3H6Cl2
IUPAC Name:
1,3-dichloropropane
Test material form:
liquid
Specific details on test material used for the study:
No data available

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
ca. 2
Temp.:
25 °C
pH:
7

Applicant's summary and conclusion

Conclusions:
Octanol/water partition coefficient is log Pow = 2.0