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Ecotoxicological information

Short-term toxicity to fish

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Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
December 19-23, 1983
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Qualifier:
equivalent or similar to
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
Qualifier:
equivalent or similar to
Guideline:
EPA OPP 72-1 (Fish Acute Toxicity Test)
GLP compliance:
not specified
Analytical monitoring:
yes
Details on sampling:
- Concentrations: 0.72, 1.1, 1.69, 2.60, 4.00 mg/L (nominal)
- Sampling method: sampling at approx mid-depth at 0, 24, 48, 72 and 96 hr
- Sample storage conditions before analysis:All samples were analyzed immediately or adequately preserved for later analysis.
Vehicle:
no
Test organisms (species):
Pimephales promelas
Details on test organisms:
TEST ORGANISM
- Common name:Fathead minnow
- Strain:
- Source:U.S. EPAenvironmental research lab-Duluth and University of Wisconsin-Superior.
- Age at study initiation (mean and range, SD): 34 Day
- Length at study initiation (length definition, mean, range and SD): 22.8 mm
- Weight at study initiation (mean and range, SD): 0.157 grams
- Method of breeding:natural spawn/fertilized embryos attached to subtrates, removed dailty and hatched in temp controlled bath
- Maintenance of the brood fish:

ACCLIMATION not specified
- Acclimation period:
- Acclimation conditions (same as test or not):
- Type and amount of food during acclimation:
- Feeding frequency during acclimation:
- Health during acclimation (any mortality observed):


FEEDING DURING TEST no feeding during test
Test type:
flow-through
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 d
Hardness:
45.3 mg/L as CaCO3
Test temperature:
24.2 C
pH:
7.58 (+/-0.3)
Dissolved oxygen:
6.5 (+/-0.06)
Reference substance (positive control):
not specified
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
1.09 mg/L
Nominal / measured:
meas. (initial)
Conc. based on:
test mat.
Basis for effect:
mortality
Validity criteria fulfilled:
yes
Conclusions:
The 96 hr LC50 for fathead minnows exposed to n-hexyl acrylate is 1.09 mg/L.

Description of key information

Key value for chemical safety assessment

LC50 for freshwater fish:
1.09 mg/L

Additional information