Registration Dossier

Environmental fate & pathways

Biodegradation in water and sediment: simulation tests

Administrative data

Endpoint:
biodegradation in water and sediment: simulation tests
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: study with acceptable limitations

Data source

Reference
Title:
No information
Author:
Corbett, M. D. and Corbett, B. R., Metabolism of 4-Chloronitrobenzene by the Yeast Rhodosporidium sp., Applied and Environmental Microbiology 41, 942-949 (1981)

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
1-chloro-4-nitrobenzene
EC Number:
202-809-6
EC Name:
1-chloro-4-nitrobenzene
Cas Number:
100-00-5
Molecular formula:
C6H4ClNO2
IUPAC Name:
1-chloro-4-nitrobenzene
Details on test material:
Test substance: no data

Study design

Oxygen conditions:
aerobic
Inoculum or test system:
other: other fungi: Rhodosporidium sp.
Duration of test (contact time):
14 d
Initial test substance concentration
Initial conc.:
0.1 mmol/L
Based on:
test mat.

Results and discussion

% Degradation
% Degr.:
> 90
Sampling time:
10 d
Transformation products:
yes
Details on results:
Degradation products (CAS No./EC No./EINECS Name): 4-chloro-2-hydroxyacetanilide
Degradation products (CAS No./EC No./EINECS Name): 106-47-8 203-401-0 4-chloroaniline
Degradation products (CAS No./EC No./EINECS Name): 539-03-7 208-707-8 4'-chloroacetanilide
Degradation products (CAS No./EC No./EINECS Name): 932-98-9 213-263-3 4-chloronitrosobenzene

Any other information on results incl. tables

2 degradation routes postulated after analysis of metabolic products. Major final metabolites are 4-chloroacetanilide and 4-chloro-2-hydroxyacetanilide.

Applicant's summary and conclusion

Conclusions:
Interpretation of results: other: biotic reduction