Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 275-532-1 | CAS number: 71487-01-9
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 123 (Partition Coefficient (1-Octanol / Water), Slow-Stirring Method)
- GLP compliance:
- no
- Type of method:
- other: HPLC-ELSD was used to determine the Test Item in the 1-octanol phase and a UV-VIS Spectrophotometer for the water phase samples,
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- The commercial product containing the "substance", Quaternary ammonium compounds, di-C12-18-alkyldimethyl, nitrites, CAS Number 71487 -01 -9, EC Number 275 -532 -1, in organic solvents, methanol and isopropanol (ca. 32%) was utlised for this study. Prior to this study being undertaken, these solvents were removed by, firstly, leaving the sample under a stream of nitrogen to remove the majority of the solvent(s) and, secondly, evaporating the remaining residual solvent(s) under vacuum at 60 degress C to constant dried weight of the test item. After solvent removal the substance was identified to be a yellow viscous liquid / wax like solid.
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- ca. 2.75
- Temp.:
- 25 °C
- pH:
- 7
- Conclusions:
- The Log Pow values for each C-chain at each sampling time have been recorded and are determined to be 2.7-2.8. Given the known carbon chain length distribution a log Pow value of 2.75 is determined to be representative of the substance.
- Executive summary:
The partition coefficient of the test item (Quaternary ammonium compounds, di-C12-18-alkyldimethyl, nitrites, CAS Number 71487-01-9, EC Number 275-532-1) was investigated in a study that was conducted according to OECD Guideline 123 (Partition Coefficient (1-Octanol / Water), Slow-Stirring Method).
This study is assigned a reliability score of 1 in accordance with the criteria for assessing data quality set forth by Klimisch et al (1997).
The Log Pow values for each C-chain at each sampling time have been recorded and are determined to be 2.7-2.8. Given the known carbon chain length distribution a log Pow value of 2.75 is determined to be representative of the substance.
Reference
Description of key information
The partition coefficient of the test item (Quaternary ammonium compounds, di-C12-18-alkyldimethyl, nitrites, CAS Number 71487-01-9, EC Number 275-532-1) was investigated in a study that was conducted according to OECD Guideline 123 (Partition Coefficient (1-Octanol / Water), Slow-Stirring Method).
This study is assigned a reliability score of 1 in accordance with the criteria for assessing data quality set forth by Klimisch et al (1997).
The Log Pow values for each C-chain at each sampling time have been recorded and are determined to be 2.7-2.8. Given the known carbon chain length distribution a log Pow value of 2.75 is determined to be representative of the substance.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 2.75
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
