Trihexylamine

Melting point / freezing point

Administrative data

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 23-02-2018 to 25-07-2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2018

Report date:

2018

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Deviations:

no

Test guideline 3

Qualifier:

according to guideline

Guideline:

other: ISO 11357-1. (2009). Plastics -- Differential Scanning Calorimetry (DSC) – Part 1: General principles. CEN, Bruxelles

Deviations:

no

Test guideline 4

Qualifier:

according to guideline

Guideline:

other: ISO 11357-3. (2013). Plastics -- Differential Scanning Calorimetry (DSC) – Part 3: Determination of temperature and enthalpy of melting and crystallization. CEN, Bruxelles

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Test material

Test material information

Constituent 1

Reference substance name:

Trihexylamine

EC Number:

203-062-9

EC Name:

Trihexylamine

Cas Number:

102-86-3

Molecular formula:

C18H39N

IUPAC Name:

trihexylamine

Results and discussion

Melting / freezing point

Key result

Melting / freezing pt.:

< -20 °C

Atm. press.:

968 hPa

Decomposition:

no

Remarks on result:

other: Mean of 2 determinations

Any other information on results incl. tables

Results of this study are considered valid as the following criteria were met:

-       The crucible was visually checked and no degradation was observed during the study. By opening it, it appeared that there was no test item left in the crucible.

-       The temperature difference obtained between the two determinations is less than 0.5°C up to 326.85°C and less than 2°C up to 1000°C.

-       The melting point obtained on the reference substance, Indium, is included in the checking chart limits.

-       The corrected sensitivity, i.e. the enthalpy measured during the melting of indium, does not differ by more than 10% from the expected value.

Applicant's summary and conclusion

Conclusions:

The melting point of the substance was determined as <– 20 °C.

Executive summary:

A study was performed to determine the melting point of the test item. The method used was Differential Scanning Calorimetry (DSC) and the test was according to Regulation EC No. 440/2008 Method A.1 and OECD Test Guideline 102 , "Melting Point/Melting Range" and following GLP. In this method, two crucibles were put in the apparatus furnace under inert atmosphere (helium) at atmospheric pressure. One crucible contained the test item, the other was empty and considered as the reference. A specific temperature program was applied. The crucibles were linked to two thermocouples fixed on the TG-DSC sample carrier. Heat flow differences between the two crucibles and mass variation were recorded on a thermogram. A cooling system using liquid nitrogen allowed experiments with low temperatures down to -120°C. Two trials were conducted and corresponding thermograms were obtained, giving the following results:

Trial 1: <-20°C at 968 hPa; Trial 2: <-20°C at 968 hPa.

The melting point values respect validity criteria. Moreover, the melting point of the Indium respects the checking cards limits (156.5°C for a reference value of 156.6°C) so as its enthalpy (30.96 J/g for a reference value of 28.6 J/g).

The melting point of the substance was determined as < – 20.0 °C.