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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
calculation (if not (Q)SAR)
Remarks:
estimated by calculation
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model, but not (completely) falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
substance is rapidly hydrolyzed

Data source

Reference
Reference Type:
other: calculation
Title:
No information
Author:
Advanced Chemistry Development
Year:
2011
Bibliographic source:
Advanced Chemistry Development Software V11.02

Materials and methods

Principles of method if other than guideline:
calculation

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethyl methacrylate
EC Number:
224-116-8
EC Name:
2-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethyl methacrylate
Cas Number:
4203-89-8
Molecular formula:
C14H23NO3
IUPAC Name:
2-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethyl methacrylate
Test material form:
liquid

Results and discussion

Bioaccumulation factor
Temp.:
25 °C
Type:
other: log BCF
Value:
1.72 dimensionless
Remarks on result:
other: calc for pH 1-10
Remarks:
Note: substance is rapidly hydrolyzed

Applicant's summary and conclusion

Validity criteria fulfilled:
not applicable
Remarks:
calculation
Conclusions:
Calculation is an estimate - model does not take hydrolysis into account, the substance rapidly hydrolyzes. Calculated log BCF = 1.72 for pH 1-10 @ 25 oC
Executive summary:

Calculation is an estimate - model does not take hydrolysis into account, the substance rapidly hydrolyzes.  Calculated log BCF = 1.72 for pH 1-10 @ 25 oC