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Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
June - September 2017
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
no
Type of method:
flask method
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 103901
- Expiration date of the lot/batch: 1 February 2019
Key result
Water solubility:
1.58 g/L
Conc. based on:
test mat. (dissolved fraction)
Incubation duration:
> 1 - <= 3 d
Temp.:
20 °C
pH:
7
Remarks on result:
completely miscible

SP02 (trade name: 50HMIC)

     Measurements after 100x dilution in distilled water          Non-diluted test solutions
 sample  Abs268nm  c (mM)  pH  mM  g/l
 1  0.5516  0.098  7  9.77  1.65
 2  0.4985  0.088  7  8.8  1.49
 3  0.5374  0.095  7  9.51  1.61
      Average 9.36   1.58
Conclusions:
The water solubility of SP02 is 1.58 g/L at 20 °C as determined by the Flask Method where the analytic technique of UV/vis absorption spectroscopy was used to determine concentrations.
Executive summary:

The water solubility of test item SP02 (trade name: 5OHMIC) is 1.58 g/L at 20 °C as determined by the Flask Method, using UV/Vis absorption spectroscopy to determine concentrations of SP02 in water.

Description of key information

The water solubility of test item SP02 (trade name: 5OHMIC) is 1.58 g/L at 20 °C as determined by the Flask Method, using UV/Vis absorption spectroscopy to determine concentrations of SP02 in water.

Key value for chemical safety assessment

Water solubility:
1.58 g/L
at the temperature of:
20 °C

Additional information