Registration Dossier

Physical & Chemical properties

Water solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018-01-31 - 2018-04-19
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reason / purpose:
reference to same study
Reason / purpose:
reference to same study
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
yes
Type of method:
flask method
Key result
Water solubility:
40.7 mg/L
Conc. based on:
test mat.
Incubation duration:
>= 0 - <= 96 h
Temp.:
20 °C
Remarks on result:
other: pH value not stated
Details on results:
OECD 105 Water Solubility was determined for the test sample based on a saturation equilibrium using the flask equilibration method. Total carbon analysis was performed within 1 hour of the test sample cooling to 20 °C (for time 0) and then at 24 and 96 hours. Triplicate samples were measured, each in duplicate. The test result graph shows the determinations for each time point and the respective mean and standard deviation. Horizontal line fit determined the equilibration point to be 40.7 ppm with a 95 % confidence interval of +/-10 ppm at each of three time-points (1, 24, 96 hrs).
Conclusions:
Water solubility was determined at quilibration point to be 40.7 ppm with a 95 % confidence interval of +/-10 ppm at each of three time-points (1, 24, 96 hrs).
Executive summary:

A study was conducted to determine the water solubility of the test-sample according to GLP and OECD Guideline 115.

OECD 105 Water Solubility was determined for the test sample based on a saturation equilibrium using the flask equilibration method. Total carbon analysis was performed within 1 hour of the test sample cooling to 20 °C (for time 0) and then at 24 and 96 hours. Water solubility was determined at quilibration point to be 40.7 ppm with a 95 % confidence interval of +/-10 ppm at each of three time-points (1, 24, 96 hrs).

Description of key information

A study was conducted to determine the water solubility of the test-sample according to GLP and OECD Guideline 115.

OECD 105 Water Solubility was determined for the test sample based on a saturation equilibrium using the flask equilibration method. Total carbon analysis was performed within 1 hour of the test sample cooling to 20 °C (for time 0) and then at 24 and 96 hours. Water solubility was determined at quilibration point to be 40.7 ppm with a 95 % confidence interval of +/-10 ppm at each of three time-points (1, 24, 96 hrs).

Key value for chemical safety assessment

Water solubility:
40.7 mg/L
at the temperature of:
20 °C

Additional information