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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
31 March 2017 - 13 April 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Deviations:
not specified
Qualifier:
according to guideline
Guideline:
other: CIPAC MT187
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
GLP compliance:
yes (incl. QA statement)
Type of method:
Laser scattering/diffraction
Type of particle tested:
primary particle
Type of distribution:
volumetric distribution
Specific details on test material used for the study:
Batch/Lot Number: 150205
Appearance: Blue powder
Purity: As a UVCB purity is considered as 100%
Mass median aerodynamic diameter:
ca. 83.346 µm
Geometric standard deviation:
ca. 0.025
Key result
Percentile:
D10
Mean:
ca. 8.551 µm
St. dev.:
0.076
Key result
Percentile:
D50
Mean:
ca. 75.028 µm
St. dev.:
1.319
Key result
Percentile:
D90
Mean:
ca. 263.823 µm
St. dev.:
5.384
No.:
#1
Size:
< 10 µm
Distribution:
ca. 11.89 %
Conclusions:
Analysis using dry powder module average (μm)
Volume Weighted mean: 110.799
Median (d.50): 75.028
Mode: 122.855
MMAD: 83.346
10% of material is < 8.551
50% of material is < 75.028
90% of material is < 263.823
By volume of sample was seen to be < 10.00 μm: 11.89%

Description of key information

Analysis using dry powder module average (μm)

Volume Weighted mean 110.799

Median (d.50) 75.028

Mode 122.855

MMAD 83.346

10% of material is < 8.551

50% of material is < 75.028

90% of material is < 263.823

By volume of sample was seen to be < 10.00 μm 11.89%

Additional information