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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

Currently viewing:

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
publication
Title:
Range-Finding toxicity data: List VII
Author:
Smyth
Year:
1969
Bibliographic source:
Am. Ind. Hyg. Assoc. J., 1969, 30:5, 470-476

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 401 (Acute Oral Toxicity)
Deviations:
no
GLP compliance:
not specified
Test type:
standard acute method
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Chromium trichloride
EC Number:
233-038-3
EC Name:
Chromium trichloride
Cas Number:
10025-73-7
Molecular formula:
Cl3Cr
IUPAC Name:
Chromium trichloride
Test material form:
liquid

Test animals

Species:
rat
Strain:
other: Carworth-Wistar
Sex:
male/female

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
water
Control animals:
no

Results and discussion

Effect levels
Key result
Sex:
male/female
Dose descriptor:
LD50
Effect level:
3 250 mg/kg bw
Based on:
test mat.
Remarks on result:
other: chromium trinitrate nonahydrate

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met