Registration Dossier
Registration Dossier
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EC number: 480-310-4 | CAS number: -
Adsorption / desorption
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
ADONA is an ionisable substance which will dissociate in water, forming ammonium (cation) and DONA (anion). Koc of the DONA anion was assessed by HPLC (OECD Guideline 121), using a single, isocratic mobile phase buffered at pH 7.1. DONA has a pKa of 1.8 (in 1:1 water:acetonitrile) and will remain in anionic form at all environmentally relevant pH values 1 . Therefore, the HPLC results are generally applicable and provide information on DONA anion sorption. DONA anion eluted before the least-retained reference compound (acetanilide, log Koc 1.25) and was assigned an upper limit log Koc ≤1.3. ADONA has a low potential for adsorption and further testing is not necessary.
1 A summary of the DONA pKa study can be found in the information included with REACH registration of DONA; REACH Registration number 01-2119991106-35-0000 (10 July 2013)
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