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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

The LD50of the test item “BF3-piperidine-complex” is higher than 5 mg/kg body weight and lower than 50 mg/kg body weight after single oral administration to Wistar rats.

Based on Annex 2d Test Procedure with a Starting Dose of 50 mg/kg body weight of OECD Guideline 423 it can be concluded that the test item “BF3-piperidine-complex” is according to GHScriteria classified in Category 2 with a LD50cut off value 25 mg/kg body weight, after single oral administration to Wistar rats

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
adverse effect observed
Dose descriptor:
LD50
Value:
25 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Justification for classification or non-classification

The LD50of the test item “BF3-piperidine-complex” is higher than 5 mg/kg body weight and lower than 50 mg/kg body weight after single oral administration to Wistar rats.

Based on Annex 2d Test Procedure with a Starting Dose of 50 mg/kg body weight of OECD Guideline 423 it can be concluded that the test item “BF3-piperidine-complex” is according to GHScriteria classified in Category 2 with a LD50cut off value 25 mg/kg body weight, after single oral administration to Wistar rats