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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

biodegradation in water: ready biodegradability
Type of information:
calculation (if not (Q)SAR)
Migrated phrase: estimated by calculation
Adequacy of study:
key study
2 (reliable with restrictions)

Data source

Reference Type:
other: software program
Estimation Programs Interface (EPI) Suite™ v3.20 for Microsoft® Windows
Bibliographic source:
, U.S. Environmental Protection Agency, Washington, DC, U.S.A.

Materials and methods

Test guideline
no guideline followed
Principles of method if other than guideline:
Estimated with BIOWIN v4.10
GLP compliance:

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(2-hydroxyethoxy)ethyl 2-hydroxypropyl 3,4,5,6-tetrabromophthalate
EC Number:
EC Name:
2-(2-hydroxyethoxy)ethyl 2-hydroxypropyl 3,4,5,6-tetrabromophthalate
Cas Number:
Molecular formula:
C15H15Br4O7 (one ring component) C8 H2 Br4 O4 . C4 H10 O3 . C3 H8 O2 Unspecified reaction product of the three components
2-(2-hydroxyethoxy)ethyl 2-hydroxypropyl 3,4,5,6-tetrabromophthalate

Study design

Oxygen conditions:
Inoculum or test system:
other: see EPIwin
Duration of test (contact time):
4 wk
Initial test substance concentration
Initial conc.:
other: not applicable
Based on:
other: Reference Substance

Results and discussion

% Degradation
Remarks on result:
other: See below

Any other information on results incl. tables

Mode of Degradation in Actual Use

STP Fugacity Model

BIOWIN (v4.10)

Primary sludge: 12.96%, Waste Sludge 9.73%, Total Biodegradation 0.26%, Total Removal 22.95%, Final Water Effluent 77.05%

Linear Model: Does Not Biodegrade Fast

Non-Linear Model: Does Not Biodegrade Fast

Ultimate Biodegradation Timeframe: Months

Primary Biodegradation Timeframe: Weeks

MITI Liner Model: Biodegrades Fast

MITI Non-Linear Model: Does Not Biodegrade Fast

Anaerobic Model: Biodegrades Fast

Ready Biodegradation Prediction: NO

Applicant's summary and conclusion

Validity criteria fulfilled:
not applicable
Interpretation of results:
under test conditions no biodegradation observed
The reference substanced is not expected to be readily biodegradable.
Executive summary:

The reference substanced is not expected to be readily biodegradable.