Registration Dossier
Registration Dossier
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EC number: 208-594-5 | CAS number: 534-22-5
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- No data
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Remarks:
- No data on GLP. Near guideline study. Reliable with restrictions. Deficiencies : i) only the results (EC0 and EC50) were reported, without underlying data on concentration response; ii) the test duration is not long enough; iii) data on analytical monitoring of 2-methylfuran are lacking.
Data source
Reference
- Reference Type:
- publication
- Title:
- Ergebniss der Schadwirkung wassergefaehrdender Stoffe gegen Daphnia magna in einem weiterentwickelten standardisierten Testverfahren.
- Author:
- Bringmann G & Kuehn R
- Year:
- 1 982
- Bibliographic source:
- Z. Wasser- Abwasser Forsch., Vol. 15, No. 1, pp. 1-6.
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2-methylfuran
- EC Number:
- 208-594-5
- EC Name:
- 2-methylfuran
- Cas Number:
- 534-22-5
- Molecular formula:
- C5H6O
- IUPAC Name:
- 2-methylfuran
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 24 h
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 24 h
- Dose descriptor:
- EC0
- Effect conc.:
- 332 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 888 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The toxicity of the test substance towards Daphnia was assessed over 24h. The EC0 (24h) is 332 mg/L and EC50 (24h) is 888 mg/L.
- Executive summary:
The toxicity of the test substance towards Dapnnia after 24h exposure, was assessed. The study was performed similar to a OECD 202. The effect levels for 2 -methylfuran were measured: EC0 (24h) = 332 mg/L and EC50 (24h) = 888 mg/L.
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