Reaction mass of 4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane and Orthophosphoric acid, oligomeric reaction products with 4,4'-isopropylidenediphenol -1-chloro-2,3-epoxypropane co-oligomer

Partition coefficient

Link to relevant study record(s)

Reference

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)

Version / remarks:

2004

Deviations:

no

GLP compliance:

no

Type of method:

HPLC method

Partition coefficient type:

octanol-water

Analytical method:

high-performance liquid chromatography

Key result

Type:

log Pow

Partition coefficient:

> 6.5

Temp.:

25 °C

Remarks on result:

other: pH not relevant

Details on results:

The test item solution was injected twice to the test equipment and the retention time of the test item was measured. As many peaks were detected from the test item solution, nine peaks with peak area percentages of more than 1% of total peak area on the chromatogram were selected as the analytical targets. Each peak was named as peak 1 to peak 9 in order of the retention time. The log Pow was calculated for each peak, resulting in a range of log Pow values of 1.2 to > 6.5. In a worst case assumption, the highest value is used in the safety assessment.


For individual results see attached document "Table - Individual Test Results Log Pow.pdf".

Description of key information

Log Pow > 6.5 at 25°C (OECD 117)

Additional information

Nine peaks was detected. The retention times ranged from about 3 to 61 minutes, resulting in log Pow values from 1.2 to > 6.5. In a worst case assumption, the highest value is used in the safety assessment.