Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

Taking into account the Guinea pig maximisation test (in vivo) with BRUGGOLITE FF6 , the weight of evidence analysis (Read-across from structurally related substances) indicates that BLANCOLEN HP is devoid of any skin sensitation.

The skin sensitisation was tested according to OECD 406 with a 10 % solution respectively a 75:25 mixture of the test substance solution with vaseline. No skin irritation was observed, not any sensitisation reaction was registered and the skin fold thickness did not increase.

Taking into account a in-vivo-study with albino rats with BRUGGOLITE FF6 , the weight of evidence analysis (Read-across from structurally related substances) indicates that the test item is devoid of any acute dermal irritation/corrosion.


Migrated from Short description of key information:
Skin sensitisation: no skin irritation (dermal induction); no sensitisation reaction; no increase in skin fold thickness

Justification for classification or non-classification