Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Skin irritation/corrosion:

One in vitro studies are available which was performed to evaluate test item ability to induce skin corrosion using a human skin model according to OECD 431 (2016). The test item is corrosive in the in vitro skin corrosion test under the experimental conditions described in this report.

 

Eye irritation:

Bovine Corneal Opacity and Permeability test (BCOP test) was performed based on the most recent OECD guideline 437. The test item induced serious eye damage through both endpoints, resulting in a mean in vitro irritancy score of 127 after 4 hours of treatment.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (corrosive)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irreversible damage)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Justification for classification or non-classification

Skin irritation/corrosion:

The test item is corrosive in the in vitro skin corrosion test

According to Regulation (EC) No 1272/2008, section 3.2.2.1 and Table 3.2.1, this substance should be classified as Category 1: Corrosive.

 

Serious eye damage/eye irritation:

Irritating, IVIS=127

According to Regulation (EC) No 1272/2008, section 3.3.2 and Globally Harmonized System of Classification and Labelling of Chemicals (GHS): United Nations Publications: New York & Geneva, (UN 2003), this substance should be classified as category 1.