Registration Dossier

Ecotoxicological information

Short-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1985
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
Reason / purpose:
reference to same study
Qualifier:
according to
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
Deviations:
yes
Remarks:
slight modifications, however no further specification of deviations
GLP compliance:
not specified
Analytical monitoring:
not specified
Details on sampling:
not specified
Vehicle:
not specified
Details on test solutions:
The test solution was prepared fresh each day.
Test organisms (species):
Poecilia reticulata
Details on test organisms:
not specified
Test type:
semi-static
Water media type:
freshwater
Remarks:
Information on chemical composition of the test media are given in Leeuwen, C:J and Maas, H. Enviromental Pollution (Series A) 37 (1985) 105-115
Total exposure duration:
96 h
Remarks on exposure duration:
not specified
Post exposure observation period:
not specified
Hardness:
not specified
Test temperature:
not specified
pH:
not specified
Dissolved oxygen:
not applicable
Salinity:
not specified
Conductivity:
not specified
Nominal and measured concentrations:
not specified
Details on test conditions:
not specified
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
0.09 mg/L
Nominal / measured:
nominal
Details on results:
not specified
Results with reference substance (positive control):
not specified
Reported statistics and error estimates:
95%-confidence interval reported: 0.06 - 0.18 mg/L
Validity criteria fulfilled:
not applicable
Conclusions:
A 96-hour LC50 was determined to be 0.09 mg/L for P. reticulata. The 95% confidence interval is calculated to be 0.06 - 0.18 mg/L.
Executive summary:

The study was carried out according to OECD Guideline 203 with slight modifications. The 96-hour LC50 was determined to be 0.09 mg/L for Poecilia reticulata. The 95 % confidence interval is calculated to be 0.06 - 0.18 mg/L.

Description of key information

LC50 (96h) = 0.09 mg/L for Poecilia reticulata (OECD Guideline 203 with slight modifications)

Key value for chemical safety assessment

LC50 for freshwater fish:
0.09 mg/L

Additional information

The study was carried out according to OECD Guideline 203 with slight modifications. The 96-hour LC50 was determined to be 0.09 mg/L nominal for Poecilia reticulata. The 95 % confidence interval is calculated to be 0.06 - 0.18 mg/L.