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Physical & Chemical properties

Surface tension

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Endpoint:
surface tension
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
weight of evidence
Justification for type of information:
REPORTING FORMAT FOR THE CATEGORY APPROACH
Registered substance (as identified in Section 1.1 identification) has similar chemical structure as the others members of the Category "Amino Acid Alkyl Amides, Sodium or
Potassium Salts" (the source chemicals).

The category “Amino Acid Alkyl Amides, Sodium or Potassium Salts” has been developed and evaluated to cover the assessment of the intrinsic properties of several similar
substances within the context of REACH Regulation. The Category includes sodium or potassium salts of amino acid alkyl amides, with a carbon chain length range of C6-C16 and an
aminoacidic pool of not selected aminoacids reflecting the natural distributions of aminoacids in various vegetables and cereals.


1. HYPOTHESIS FOR THE CATEGORY APPROACH (ENDPOINT LEVEL)
The Category has been built up considering the common chemical structure of its members. They are UVCB substances and they share the following features:
- they are salts of amino acid alkyl amides
- they are sodium or potassium salts
- the carbon chain length ranges between C6 and C16
- the carbon chain derives from cocoyl or lauroyl fatty acids
- the aminoacidic part of the molecules comes from a pool of aminoacids
- the aminoacids pool reflects the natural distributions of aminoacids in various vegetables and cereals.

Overall, the Category was formed on the hypothesis that substances sharing this common chemical structure can be considered analogues and can share intrinsic properties too. No
trends in properties is expected, except for those physicochemical properties depending on the carbon chain length.

2. CATEGORY APPROACH JUSTIFICATION
These substances share (i) eye damage and (ii) the absence of significant systemic toxicity.
Key result
Surface tension:
> 23.65 - <= 30.8 mN/m
Remarks on result:
other: Surface tension values are available for category members: (i) 23.65 mN/m, (ii) 30.8 mN/m.
Remarks:
Surface tension values are available for category members: (i) 23.65 mN/m, (ii) 30.8 mN/m.
Conclusions:
A collection of the surface tension values is available for category members. Considering these values, registered substance has a surface tension between 23.65 and 30.8 mN/m.
Executive summary:

The category “Amino Acid Alkyl Amides, Sodium or Potassium Salts” was formed on the hypothesis that substances sharing common chemical structure can be considered analogues and can share intrinsic properties too.

Based on this assumption, this property may be assessed using available data  for the category members.

The category has been assessed for members characterized by:

- sodium or potassium salts

- the carbon chain length ranges between C6 and C16

- the aminoacids pool reflects the natural distributions of aminoacids in various vegetables and cereals.

Endpoint:
surface tension
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008-11-25 to 2010-06-28
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study performed following OECD guideline GLP study
Qualifier:
according to guideline
Guideline:
OECD Guideline 115 (Surface Tension of Aqueous Solutions)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.5 (Surface Tension)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
ring method
Specific details on test material used for the study:
Identification of the test item LCE08116
Identification of the flask LCE08116
Name PROTEOL APL Batch no. 824800002
Appearance Colourless to slightly colored (yellow) limpid
liquid
Composition sodium cocoyl apple amino acids
CAS No. unknown EINECS-No. unknown
Molecular formula unknown
Molecularweight 381 g/mol, based on disodium cocoyl glutamate
Purity not stated
Homogeneity not stated
Vapour pressure not stated
Stability unknown
Solubility water> 1 g/L(395g/L),Solubility in n-Octanol <1g/L
Solubility in ethanol , acetone, DM50, CH3CN unknown
Production date 04. September 2008
Expiry date 04. September 2011
Storage room temperature 20 ± 5°C, dark
Key result
Surface tension:
30.8 mN/m
Temp.:
20.2 °C
Conc.:
1 g/L
Conclusions:
The mean surface tension of the test item at 1 g/L in demineralized water was 30.8 ± 0.6 mN/m (corrected value).
The test item was considered as surface-active in our experimental conditions.
Executive summary:

SURFACE TENSION

In compliance with Commission Directive 92/69/EEC, Commission Regulation (EC) No. 440/2008 EC A5 method (2008) and OECD Guideline No. 115 (1995)

The mean surface tension of the test item at 1 g/L in demineralized water was 30.8 ± 0.6 mN/m (corrected value). The test item was considered as surface-active in our experimental conditions.

Endpoint:
surface tension
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Principles of method if other than guideline:
- Principle of test:

The objective is to check that Proteol SAV 50S matches with the following definition of organic surface-active agents:
If mixed with water at 20 °C and at a 0.5 % concentration; after one hour at the same temperature:
-the product is a transparent or translucent liquid or a stable emulsion without separation of the insoluble material
-the surface tension of water is lowered to 4.5E-2 N/m (45 dynes/cm) or less.

- Short description of test conditions:

Measures at 20°C +/- 1°C with a platinium plate on the tensiometer KRUSS K12.

- Parameters analysed / observed:

Measures number: 100
Maximum time: 200 s
The experience stopped automatically when the standard deviation is equal to 0 mN/m.


GLP compliance:
not specified
Type of method:
plate method
Surface tension:
>= 23.6 - <= 23.7 mN/m
Temp.:
20 °C
Conc.:
5 g/L
Conclusions:
PROTEOL SAV 50S at 20°C and at a concentration of 0,5% in water is a transparent liquid and has a surface tension of 23.65 mN/m.
Executive summary:

PROTEOL SAV 50S at 20°C and at a concentration of 0,5% in water is a transparent liquid and has a surface tension of 23.65 mN/m.

Description of key information

Category members (Amino Acid Alkyl Amides, Sodium or Potassium Salts) are surface active materials.

Key value for chemical safety assessment

Additional information

A collection of the surface tension values are available for category members. All found values are listed below.

EC number

Surface tension (mN/m)

S1 - EC: 918-984-3

30.8 mN/m

S2 - EC: 927-837-2

23.65 mN/m

 

Overall, registered substance has a surface tension between 23.65 and 30.8 mN/m.