Registration Dossier

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Description of key information

Category members (Amino Acid Alkyl Amides, Sodium or Potassium Salts) do not have genetic toxicity.

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (negative)

Genetic toxicity in vivo

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Justification for classification or non-classification

A collection of the mutagenicity data are available for category members. All found values are listed below.

EC number

Mutagenicity

S1 - EC: 918-984-3

The test substance does not induce reverse mutation on four Salmonella typhimurium strains and one Escherichia coli WP2(uvrA-) (pKM 101) strain, according to the OECD guideline n° 471 and to the method B13/B14 of the directive CE/2000/32.

S2 - EC: 927-837-2

MUTAGENIC and NON-PROMUTAGENIC under the test conditions.

 

Overall, the mutagenic/clastogenic activity may be excluded for the registered substance.

According to Regulation (EC) n. 1272/2008, the registered substance should not be classified for the genetic toxicity. However, because the only available data are on bacterial systems, this property is been considered as inconclusive for the classification.