9-Octadecenoic acid (Z)-, reaction products with diethylenetriamine, di-Me sulfate-quaternized

Endpoint summary

Description of key information

Six studies in total are included for consideration of the biodegradation potential of the test substance 9-Octadecenoic acid (Z)-, reaction products with diethylenetriamine, di-Me sulfate-quaternized. Only one study, a screening study, used the test substance itself, in which the test substance was found to have 0% biodegradation after 28 days and was classified as not readily biodegradable. Four other screening tests are included, and one simulation study (design similar to an OECD 303) which assessed the biodegradation of two different read-across substances, although some studies comprised of more than one constituent. Variable results are presented, with very limited biodegradation observed in three studies and significant biodegradation observed in two others. A summary of the data is presented below in Table 1, which has been used in a weight of evidence approach. For the weight of evidence approach the number of studies demonstrating ready biodegradation has been totalled and the number of studies demonstrating the substance is not readily biodegradable have been totalled. Studies with read across substances have been provided a weight of 1 and studies on the actual test substance have been provided a weight of 2.

 

Based on the above method the evidence for the test substance being readily biodegradable is 2 and the evidence for the test substance not being readily biodegradable is 5. In summary the test substance is classified as not readily biodegradable.

Additional information

Table 1. Weight of evidence evaluation of all biodegradation data (screening and simulation tests)

Test reference	Test substance or read across	Substance tested (or multiple constituents)	Result	Weighting
WOE Biodegradation in water: screening tests.937-237-2_OECD 301 E_Target	Read across	Fatty acids, C16-18 (even numbered) and C18 unsatd., reaction products with diethylene triamine, di-... / 937-237-2;   Imidazolium compounds, 2-(C15-17(odd numbered), C17-unsatd. alkyl)-1-[2-(C16-18(even numbered), C18-...;   Partially unsaturated IQAC, DMS quaternised	Readily biodegradable and fulfilling the 10 -d window criterion (76% degradation after 7 d).	1
WOE Biodegradation in water: screening tests: 931-745-8_OECD 301b_Target	Read across	Imidazolium compounds, 2-C17-unsatd.-alkyl-1-(2-C18-unsatd. amidoethyl)-4,5-dihydro-N-methyl, Me sul... / 931-745-8;   Oleic-acid based IQAC, DMS quaternised	Not readily biodegradable (<= 12.7 % degradation after 28 d)	1
WOE Biodegradation in water: screening tests: 937-237-2_OECD301F_Target	Read across	Fatty acids, C16-18 (even numbered) and C18 unsatd., reaction products with diethylene triamine, di-... / 937-237-2	0% biodegradation after 28 days, not readily biodegradable.	1
WOE Biodegradation in water: screening tests	Test substance	Octadecenoic acid (Z)-, reaction products with diethylenetriamine, di-Me sulfate-quaternized	0% biodegradation after 28 days, and therefore, is classified as not readily biodegradable.	2
Key Biodegradation in water and sediment: simulation tests.937-237-2_OECD_Target	Read across	Fatty acids, C16-18 (even numbered) and C18 unsatd., reaction products with diethylene triamine, di-... / 937-237-2;   Imidazolium compounds, 2-(C15-17(odd numbered), C17-unsatd. alkyl)-1-[2-(C16-18(even numbered), C18-...;   Partially unsaturated IQAC, DMS quaternised	> 90% removal in a modified activated sludge unit.	1
WOE Biodegradation in water : screeening tests: 931 -745 -8 OECD310 Target	Read across	Oleic-acid based IQAC, DMS quaternised_2	10% biodegradation after 35 days, 26% after 60 days, therefire is classified as not readily biodegradable.	1