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EC number: 222-212-4 | CAS number: 3387-41-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-D (Determination of the "Ready" Biodegradability - Manometric Respirometry Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Thuj-4(10)-ene
- EC Number:
- 222-212-4
- EC Name:
- Thuj-4(10)-ene
- Cas Number:
- 3387-41-5
- Molecular formula:
- C10H16
- IUPAC Name:
- 4-methylidene-1-(propan-2-yl)bicyclo[3.1.0]hexane
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Duration of test (contact time):
- ca. 28 d
Results and discussion
- Preliminary study:
- The test vessels were filled with medium, then test item and positive control were added to the appropriate vessels and the pH in the test vessels was measured as 7.3, pH in abiotic control was adjusted to 7.2. The vessels were incubated at 22.0 ± 2.0 °C. After pH-adjustment, the inoculum was added, the vessels were connected to the OxiTop® measuring heads and they were started via the OxiTop® Controllers.
- Test performance:
- The oxygen which was consumed by the content of the vessels was measured automati-cally by the test apparatus.
After 28 days, the test was ended.
Because the test item and positive control do not contain nitrogen, presence of nitrate and nitrite was not checked.
% Degradation
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- ca. 36
- Sampling time:
- 28 d
- Details on results:
- The degree of biodegradation reached 36 % after 28 days.
The 10-day-window began on day 7 (this is stated as lag phase), at its end (day 17), 26 % were reached, staying below the pass level of 60 % given in the OECD guideline.
The degradation phase is defined as interval between the end of the lag phase to the time when 90% of the maximum level of degradation has been reached. End of the degradation phase was on day 24.
Therefore, regardless of the 10-day-window, the test item Thuj-4(10)-ene is not readily biodegradable following OECD 301F/EU C.4-D.
Applicant's summary and conclusion
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The test item Thuj-4(10)-ene was tested using a concentration of 31 mg test item/L (equiv-alent to a theoretical oxygen demand of 100.96 mg O2/L). Activated sludge was used as inoculum. The test was left running for 28 days.
All validity criteria were met. The positive control reached the pass level of 60 % on day 4 (criterion:<=14).
The following data could be determined for the test item Thuj-4(10)-ene:
10-day-window: day 7 – 17
degradation at the end of 10-day-window 26 %
degradation at the end of the test 36 %
Therefore, regardless of the 10-day-window, Thuj-4(10)-ene is classified as not readily biodegradable following OECD 301F/EU C.4-D.
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