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Physical & Chemical properties

Partition coefficient

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Endpoint:
partition coefficient
Data waiving:
study technically not feasible
Justification for data waiving:
the study does not need to be conducted because the substance decomposes
Endpoint:
partition coefficient
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
1. HYPOTHESIS FOR THE ANALOGUE APPROACH
Please see attachment read-across justification in section 13.
2. SOURCE AND TARGET CHEMICAL(S)
Please see attachment read-across justification in section 13.

3. ANALOGUE APPROACH JUSTIFICATION
Please see attachment read-across justification in section 13.

4. DATA MATRIX
Please see attachment read-across justification in section 13.
Qualifier:
according to guideline
Guideline:
other: calculated
Deviations:
not specified
GLP compliance:
no
Type of method:
other:
Partition coefficient type:
octanol-water
Type:
log Pow
Partition coefficient:
-1.75
Remarks on result:
not measured/tested
Type:
log Pow
Partition coefficient:
-1.32
Remarks on result:
not measured/tested
Endpoint:
partition coefficient
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
1. HYPOTHESIS FOR THE ANALOGUE APPROACH
Please see attachment read-across justification in section 13.
2. SOURCE AND TARGET CHEMICAL(S)
Please see attachment read-across justification in section 13.

3. ANALOGUE APPROACH JUSTIFICATION
Please see attachment read-across justification in section 13.

4. DATA MATRIX
Please see attachment read-across justification in section 13.
Reason / purpose for cross-reference:
read-across: supporting information
Qualifier:
according to guideline
Guideline:
other: measured
Deviations:
not specified
GLP compliance:
no
Type of method:
other:
Partition coefficient type:
octanol-water
Specific details on test material used for the study:
- Name of test material (as cited in study report): 2, 2"-methyliminodiethanol
- Analytical purity: pure
Type:
log Pow
Partition coefficient:
-1.08
Remarks on result:
not measured/tested
Conclusions:
log Pow -1.08

Description of key information

Testing is not technically feasible as substance is hydrolytically unstable. Log Kow of similar released substances is used  in CSA.

Key value for chemical safety assessment

Log Kow (Log Pow):
-1
at the temperature of:
25 °C

Additional information

Titanium 2,2',2''-nitrilotrisethanolate is hydrolytically unstable. When it comes in contact with water or moisture, a complete hydrolysis will take place with no significant reaction products other than triethanolamine and hydrated titanium selate. Because of rapid hydrolysis, log Kow of similar released substances is used as a key value in CSA (peer-reviewed handbook value, Verschueren, Karel, 2001).