Fatty acids, C8-10, oxybis(2-hydroxy-3,1-propanediyl) esters

Biodegradation in water: screening tests

Link to relevant study record(s)

Reference

Endpoint:

biodegradation in water: ready biodegradability

Type of information:

experimental study

Adequacy of study:

key study

Study period:

19 March - 16 April 1999

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Qualifier:

according to guideline

Guideline:

EU Method C.4-D (Determination of the "Ready" Biodegradability - Manometric Respirometry Test)

Deviations:

no

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)

GLP compliance:

yes

Oxygen conditions:

aerobic

Inoculum or test system:

activated sludge, domestic, non-adapted

Details on inoculum:

Source of activated sludge: Fresh activated sludge was collected from a municipal sewage treatment plant: Hochdahl, Germany.

Duration of test (contact time):

28 d

Initial conc.:

100 mg/L

Based on:

test mat.

Parameter followed for biodegradation estimation:

O2 consumption

Details on study design:

TEST CONDITIONS
- Test temperature: 22 +/- 1
- Continuous darkness: yes

TEST SYSTEM
- Number of culture flasks/concentration: 3

CONTROL AND BLANK SYSTEM
- Inoculum blank: 3
- Abiotic sterile control: no
- Toxicity control: yes

Reference substance:

acetic acid, sodium salt

Parameter:

% degradation (O2 consumption)

Value:

102

Sampling time:

28 d

Details on results:

Within the 10-day time window the 60% level was passed. Therefore, the test substance is regarded as readily biodegradable.

Results with reference substance:

Degradation: 85 % after 14 days, 60% pass level was reached.

Validity criteria fulfilled:

yes

Interpretation of results:

readily biodegradable

Description of key information

Readily biodegradable: 102% (O2 consumption) in 28 days (EU method C.4 D)

Key value for chemical safety assessment

Biodegradation in water:

readily biodegradable

Type of water:

freshwater

Additional information

The ready biodegradability of Fatty acids, C8-10, oxybis(2-hydroxy-3,1-propanediyl) esters (CAS 92044-91-2) was investigated according to EU method C.4 D (equivalent to OECD 301 F). The study was conducted under aerobic conditions using domestic activated sludge as inoculum. During the incubation time of 28 days the degradation was followed by determining the O2 consumption. A degradation of 102 % was determined at test termination. The 10-day window criterion was met. Hence, Fatty acids, C8-10, oxybis(2-hydroxy-3,1-propanediyl) esters can be considered as readily biodegradable according to OECD criteria.