Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
melting point/freezing point
Type of information:
other: Literature
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
review article or handbook
Title:
Etifoxine profil
Author:
not speficied
Year:
2018
Bibliographic source:
https://www.drugbank.ca/drugs/DB08986 U.S. Patent 3,725,404.

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Version / remarks:
The followed guideline is not specified
Principles of method if other than guideline:
The followed guideline is not specified
GLP compliance:
not specified
Type of method:
other: not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine
EC Number:
630-330-6
Cas Number:
21715-46-8
Molecular formula:
C17H18Cl2N2O
IUPAC Name:
6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine
Test material form:
solid: particulate/powder

Results and discussion

Melting / freezing point
Key result
Melting / freezing pt.:
ca. 90 - 92 °C
Atm. press.:
ca. 1 013 hPa

Applicant's summary and conclusion

Conclusions:
Drug bank database reports a melting point value of 90-92°C.
Executive summary:

Drug bank database reports a melting point value of 90-92°C.