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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
17 November 2014 to 21 November 2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Water solubility:
84.5 mg/L
Temp.:
20 °C
pH:
6.4
Remarks on result:
other: Mean values for 24 -72 hours, deviation (24 - 72 hours) 8 %. Temperature 20 ± 0.5 ºC.
Details on results:
Tyndall Effect was negative for all samples.

The validity criteria were met:

The concentrations did not differ by more than 15 %.

The temperature were kept constant at ± 0.5 ºC.

Water Solubility Results at 20 °C

 

Preincubation time

(hours)

Replicate No.

Test item concentration

(mg/L)

Concentration1

Mean

24

1

86.6

80.8

2

75.6

48

1

85.5

87.3

2

89.1

72

1

84.5

85.3

2

86.1

Mean (24-72 hours)

 

84.5

Deviation [%] (24-72 hours)

8

1 Mean of two injections
Conclusions:
Interpretation of results: slightly soluble (0.1-100 mg/L)
The water solubility of 1,3-dimethyl-3-phenylbutyl acetate was determined to be 84.5 mg/L at 20.0 ± 0.5 °C and pH 6.4.
Executive summary:

The water solubility of 1,3-dimethyl-3-phenylbutyl acetate was determined to be 84.5 mg/L at 20.0 ± 0.5 °C and pH 6.4. The water solubility of the test item was determined in a GLP study (2015) following OECD guideline 105. The study is considered reliable and relevant for use for this endpoint.

Description of key information

The water solubility of 1,3-dimethyl-3-phenylbutyl acetate was determined to be 84.5 mg/L at 20.0 ± 0.5 °C and pH 6.4. 

Key value for chemical safety assessment

Water solubility:
84.5 mg/L
at the temperature of:
20 °C

Additional information

The water solubility of the test item was determined in a GLP study (2015) following OECD guideline 105. The study is considered reliable and relevant for use for this endpoint.