Registration Dossier

Administrative data

Link to relevant study record(s)

Description of key information

There are no pharmacokinetic or metabolism studies available for the substance or the read-across substance, 4-methyl-4-phenylpentan-2-ol. The test item can be assumed to be absorbed by the oral, dermal, and inhalation routes of exposure, however default absorption values are used in the derivation of DNELs, according to REACH guidance R.8 page 19


Key value for chemical safety assessment

Absorption rate - oral (%):
50
Absorption rate - dermal (%):
50
Absorption rate - inhalation (%):
100

Additional information

There are no pharmacokinetic or metabolism studies available for the substance or the read-across substance, 4-methyl-4-phenylpentan-2-ol. Default values have been entered for the absorption rates for oral, dermal and inhalation routes according to REACH guidance R.8 page 19.