Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Aquatic studies for the read-across substances (formic acid, trimethylolpropane and pentaerythritol) were presented for short-term toxicity to fish, daphnia, algae and microorganisms and long-term results were available for chronic toxicity to daphnia. With regards to formic acid some ecotox data is presented for formate.

Environmentally the dominant compound with regards to relevant exposure is considered to be the formate. As such any information for the formate species is considered to be suitable for read across to formic acid in all cases.

Studies conducted using di-pentaerythritol are used as read across because di-pentaerythritol is considered to be analogous to pentaerythritol. Di-pentaerythritol and pentaerythritol have similar levels of toxicity to aquatic species, both have low log Kow values and are largely of the same structure. As such read across is considered to be valid between the two substances.

The lowest available LC50 for acute toxicity to fish is 100 mg/l, based on an experiment carried out for pentaerythritol usingOryzias latipes.

The lowest available EC50 for acute toxicity toDaphnia magnais 365 mg/l for ammonium formate.

The lowest EC50 for algae was 100 mg/l, measured based on the effect of dipentaerythritol on the growth of Scendesmus subspicatus.

The lowest endpoint (EC10) for toxicity to microorganisms was found to be 72 mg/l for formic acid.

The 21-day NOEC for reproduction inDaphnia magnawas found to be >100 mg/l for formic acid.

In the chemical safety assessment performed according to Article 14(3) in connection with Annex I section 3 (Environmental Hazard Assessment) no hazard was identified. Therefore according to REACH Annex I (5.0) exposure estimation is not necessary. Consequently, in accordance with Column 2 of REACH Annex IX, long term studies do not formally need to be conducted as all identified uses of the substance are assessed as safe for the environment (however some long term studies are available nonetheless and for the sake of completeness are presented).

Additional information