Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: Knudsen cell

Test material

Constituent 1
Chemical structure
Reference substance name:
Chondroitin disaccharide deltadi-4S sodium salt
Cas Number:
136144-56-4
Molecular formula:
C14H19NO14S•2Na
IUPAC Name:
Chondroitin disaccharide deltadi-4S sodium salt
Constituent 2
Chemical structure
Reference substance name:
α-deltaUA-[1→3]-GalNAc-6S = α-[4-deoxy-L-threo-hex-4-enopyranosyluronic acid] sodium salt-[1→3]-N-acetyl-D-galactosamine-6-sulphate
Cas Number:
136132-72-4
Molecular formula:
C14H19NO14S•2Na
IUPAC Name:
α-deltaUA-[1→3]-GalNAc-6S = α-[4-deoxy-L-threo-hex-4-enopyranosyluronic acid] sodium salt-[1→3]-N-acetyl-D-galactosamine-6-sulphate
Constituent 3
Reference substance name:
unknown metal constituents
IUPAC Name:
unknown metal constituents
Constituent 4
Chemical structure
Reference substance name:
Chloride
Cas Number:
16887-00-6
Molecular formula:
Cl
IUPAC Name:
Chloride
Constituent 5
Chemical structure
Reference substance name:
Ethanol
EC Number:
200-578-6
EC Name:
Ethanol
Cas Number:
64-17-5
Molecular formula:
C2H6O
IUPAC Name:
Ethanol
Constituent 6
Reference substance name:
unknown constituent
Molecular formula:
unknown
IUPAC Name:
unknown constituent
Constituent 7
Chemical structure
Reference substance name:
Glucuronic acid
EC Number:
229-486-4
EC Name:
Glucuronic acid
Cas Number:
6556-12-3
Molecular formula:
C6H10O7
IUPAC Name:
(2S,3S,4S,5R,6R)-3,4,5,6-Tetrahydroxyoxane-2-carboxylic acid / (2S,3S,4S,5R,6R)-3,4,5,6- Tetrahydroxyoxane-2-carboxylic acid
Constituent 8
Chemical structure
Reference substance name:
(2R,3S,5R)-3-amino-6-(hydroxyméthyl)oxane-2,4,5-triol
Cas Number:
7535-00-4
Molecular formula:
C6H13NO5
IUPAC Name:
(2R,3S,5R)-3-amino-6-(hydroxyméthyl)oxane-2,4,5-triol
Constituent 9
Reference substance name:
group of unknown constituents
Molecular formula:
unknown
IUPAC Name:
group of unknown constituents
Test material form:
solid

Results and discussion

Vapour pressure
Remarks on result:
not determinable
Remarks:
see explanation below

Any other information on results incl. tables

Four trials were conducted and five points were recorded for each trial except for the second trial where no exploitation was possible.

Log10(Vapour Pressure (Pa)) was plotted against reciprocal temperature but no linear relation was observed (correlation coefficient R² below 0.95). Therefore no value of vapour pressure was calculated at 20°C or 25°C.

Applicant's summary and conclusion

Conclusions:
In conclusion, no vapour pressure could be obtained for SODIUM CHONDROITIN SULFATE during this study.