Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference Type:
other: secondary literature
NITE - Chemical Management Field - GHS Information GHS Classification Result
Bibliographic source:
GHS-J [Internet]. National Institute of Technology and Evaluation (NITE): GHS Classification Results by the Japanese Government. Available from:

Materials and methods

Test guideline
no guideline available
GLP compliance:
not specified
Test type:
other: not specified

Test material

Specific details on test material used for the study:
not specified

Test animals

not specified
not specified
Details on test animals or test system and environmental conditions:
not specified

Administration / exposure

Route of administration:
inhalation: vapour
Type of inhalation exposure:
not specified
not specified
Details on inhalation exposure:
not specified
Analytical verification of test atmosphere concentrations:
not specified
Duration of exposure:
7 h
Remarks on duration:
not specified
not specified
No. of animals per sex per dose:
not specified
Control animals:
not specified
Details on study design:
not specified
not specified

Results and discussion

Preliminary study:
not specified
Effect levels
Key result
not specified
Dose descriptor:
Effect level:
0.955 mg/L air
Exp. duration:
4 h
not observed
Clinical signs:
other: not specified
Body weight:
not specified
Gross pathology:
not specified
Other findings:
not specified

Any other information on results incl. tables

not specified

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Besides, the s aturated vapour pressure concentration (0.722 mg/L) (converted to a 4-hour equivalent: 0.955 mg/L) exposure to rats for 7 hours resulted in no deaths, but the category could not be determined only from this data