Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 813-358-5 | CAS number: 4886-26-4
Endpoint summary
Administrative data
Description of key information
one in vitro study on estimation of LD50 and proposed starting dose for further in vivo studies is available. one in vivo study according to OECD 423 available
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 2 500 mg/kg bw
- Quality of whole database:
- The available in vitro study indicates an approximate estimated LD50 of 761-1036 mg/kg body weight. As this value is within the range of 300 - 2000 mg/kg bw. The described in vitro assay is discussed in Guidance on information requirements and Chemical safety assessment, chapter R.7-a. The available in vivo study indicates an LD50 > 2000 mg/kg bw. For endpoint conclusion reported here, a dose discriptor of LD50 = 2500 mg/kg bw is chosen in accordance with OECD Guideline 423, Annex 2.
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
The available information is conclusive but not sufficient for classification.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
