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EC number: 428-190-4 | CAS number: 68490-66-4 CUREZOL 2MA-OK
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 12 Dec 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- Version / remarks:
- ISO 13320:2009
- Deviations:
- not specified
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Ministero della Salute, Rome, Italy
- Type of method:
- Laser scattering/diffraction
- Type of particle tested:
- primary particle
- Type of distribution:
- volumetric distribution
Test material
Constituent 1
Results and discussion
Particle sizeopen allclose all
- Percentile:
- D90
- Mean:
- 3.194 µm
- St. dev.:
- 0.214
- Percentile:
- D50
- Mean:
- 1.587 µm
- St. dev.:
- 0.074
- Percentile:
- D10
- Mean:
- 0.741 µm
- St. dev.:
- 0.028
Any other information on results incl. tables
Results
The particle size distribution was determined using the laser diffraction method with dry dispersion . The particle size distribution of the test item was determined in 12 measurements. The instrument detected a bimodal grain size distribution and generated a mean value and size distributions automatically. In Table below, the results of the particle size analysis on the sample labelled as
2MAOK-PW, are reported.
Measurement |
L10D(v,0.1) [µm] |
L50D(v,0.5) [µm] |
L90D (v,0.9) [µm] |
1 |
0.732 |
1.571 |
3.175 |
2 |
0,724 |
1.572 |
3.153 |
3 |
0.729 |
1.555 |
3.068 |
4 |
0.714 |
1.528 |
3.017 |
5 |
0.726 |
1.520 |
2.961 |
6 |
0.719 |
1.511 |
2.947 |
7 |
0.745 |
1.510 |
3.068 |
8 |
0.757 |
1.746 |
3.713 |
9 |
0.809 |
1.710 |
3.379 |
10 |
0.710 |
1.634 |
3.444 |
11 |
0.769 |
1.633 |
3.238 |
12 |
0.767 |
1.605 |
3.143 |
|
|
|
|
MeanValue* |
0.741 |
1.587 |
3.194 |
Standard Deviation of the population |
0.028 |
0.074 |
0.214 |
*Mean value is calculated by the software of the apparatus Mastersizer 2000 from the entirety of data captured in each run and it is not a simple arithmetic mean.
Conclusion
According to test method ISO 13320:2009, the volume mean diameter of sample labelled as 2MAOK-PW is 1.811 µm and its 90%, 50% and 10% cumulative size distributions are 3.19 µm, 1.59 µm and 0.74 µm respectively.
Applicant's summary and conclusion
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