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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
14 March 2018 to 18 March 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
23 March 2006
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
30 May 2008
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: vapour pressure balance
Specific details on test material used for the study:
- Identification: tris(2-hydroxyethyl)methylammonium hydroxide CAS 33667-48-0
- Batch:D26-3-3-1
- Purity:47.4%
- Expiry:01 December 2018
- Storage conditions:Room temperature in the dark
Key result
Temp.:
25 °C
Vapour pressure:
0.49 Pa

Recorded temperatures, mass differences and the resulting calculated values of vapor pressure are shown in the following tables:

Run 2

Table1– Vapor Pressure Data

Temperature (ºC)

Temperature (K)

Reciprocal Temperature (K-1)

Mass Difference (µg)

Mass Difference (kg)

Vapor Pressure (Pa)

Log10Vp

-5

268.15

0.0037293

21.95

2.195e-08

0.0304722

-1.516096

-4

269.15

0.0037154

23.78

2.378e-08

0.0330127

-1.481319

-3

270.15

0.0037016

25.73

2.573e-08

0.0357198

-1.447091

-2

271.15

0.0036880

29.09

2.909e-08

0.0403844

-1.393787

-1

272.15

0.0036744

32.03

3.203e-08

0.0444659

-1.351973

0

273.15

0.0036610

34.64

3.464e-08

0.0480892

-1.317952

1

274.15

0.0036476

38.97

3.897e-08

0.0541003

-1.266800

2

275.15

0.0036344

43.62

4.362e-08

0.0605557

-1.217845

3

276.15

0.0036212

48.38

4.838e-08

0.0671638

-1.172865

4

277.15

0.0036082

53.68

5.368e-08

0.0745216

-1.127718

5

278.15

0.0035952

58.03

5.803e-08

0.0805605

-1.093878

A plot of Log10(vapor pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 2 gives the following statistical data using an unweighted least squares treatment.

Slope:

-3.24 x 103

Standard error in slope:

50.2

 

Intercept:

10.6

Standard error in intercept:

0.184

The results obtained indicate the following vapor pressure relationship:

Log10(Vp (Pa)) = -3.24 x 103/temp(K) + 10.6

The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -0.311.

Run 3

Table2– Vapor Pressure Data

Temperature (ºC)

Temperature (K)

Reciprocal Temperature (K-1)

Mass Difference (µg)

Mass Difference (kg)

Vapor Pressure (Pa)

Log10Vp

-5

268.15

0.0037293

22.07

2.207e-08

0.0306388

-1.513728

-4

269.15

0.0037154

23.08

2.308e-08

0.0320410

-1.494295

-3

270.15

0.0037016

25.81

2.581e-08

0.0358309

-1.445742

-2

271.15

0.0036880

27.47

2.747e-08

0.0381354

-1.418672

-1

272.15

0.0036744

30.26

3.026e-08

0.0420086

-1.376661

0

273.15

0.0036610

33.58

3.358e-08

0.0466176

-1.331450

1

274.15

0.0036476

38.10

3.810e-08

0.0528926

-1.276605

2

275.15

0.0036344

42.92

4.292e-08

0.0595840

-1.224871

3

276.15

0.0036212

47.19

4.719e-08

0.0655118

-1.183680

4

277.15

0.0036082

52.97

5.297e-08

0.0735359

-1.133500

5

278.15

0.0035952

58.93

5.893e-08

0.0818099

-1.087194

A plot of Log10(vapor pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 3 gives the following statistical data using an unweighted least squares treatment.

Slope:

-3.29 x 103

Standard error in slope:

97.6

 

Intercept:

10.7

Standard error in intercept:

0.357

The results obtained indicate the following vapor pressure relationship:

Log10(Vp (Pa)) = -3.29 x 103/temp(K) + 10.7

The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -0.307.

Run 4

Table3– Vapor Pressure Data

Temperature (ºC)

Temperature (K)

Reciprocal Temperature (K-1)

Mass Difference (µg)

Mass Difference (kg)

Vapor Pressure (Pa)

Log10Vp

-5

268.15

0.0037293

20.35

2.035e-08

0.0282510

-1.548966

-4

269.15

0.0037154

22.27

2.227e-08

0.0309165

-1.509810

-3

270.15

0.0037016

25.39

2.539e-08

0.0352478

-1.452868

-2

271.15

0.0036880

27.37

2.737e-08

0.0379966

-1.420256

-1

272.15

0.0036744

30.47

3.047e-08

0.0423002

-1.373658

0

273.15

0.0036610

33.77

3.377e-08

0.0468814

-1.328999

1

274.15

0.0036476

37.06

3.706e-08

0.0514488

-1.288625

2

275.15

0.0036344

42.32

4.232e-08

0.0587510

-1.230985

3

276.15

0.0036212

46.15

4.615e-08

0.0640680

-1.193359

4

277.15

0.0036082

50.63

5.063e-08

0.0702874

-1.153122

5

278.15

0.0035952

56.92

5.692e-08

0.0790195

-1.102265

A plot of Log10(vapor pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 4 gives the following statistical data using an unweighted least squares treatment.

Slope:

-3.32 x 103

Standard error in slope:

37.9

 

Intercept:

10.8

Standard error in intercept:

0.139

The results obtained indicate the following vapor pressure relationship:

Log10(Vp (Pa)) = -3.32 x 103/temp(K) + 10.8

The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -0.306.

The values of vapor pressure at 25 °C extrapolated from each graph are summarized in the following table:

Table 4            Summary of Vapor Pressure Data

Run

Log10[Vp(25 ºC)]

2

-0.311

3

-0.307

4

-0.306

Mean

-0.308

Vapor Pressure

0.493 Pa

The test item did not change in appearance under the conditions used in the determination.

Discussion

A total of 4 runs were completed for the main sequence. Equilibrium had been reached over the final 3 runs, thus, the final 3 runs have been used to determine the vapor pressure.

The results may represent rounded values obtained by calculations based on the exact raw data.

Conclusions:
The vapor pressure of the test item has been determined to be 0.49 Pa at 25 ºC.
Executive summary:

The vapor pressure of tris(2-hydroxyethyl)methylammonium hydroxide CAS 33667-48-0 has been determined to be 0.49 Pa at 25 °C, using the vapor pressure balance method, designed to be compatible with Method A.4 Vapour Pressure of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 104 of the OECD Guidelines for Testing of Chemicals, 23 March 2006.

Description of key information

The vapor pressure of the test substance has been determined to be 0.49 Pa at 25 °C, using the vapor pressure balance method, designed to be compatible with EU Method A.4 and OECD Guideline104.

Key value for chemical safety assessment

Vapour pressure:
0.49 Pa
at the temperature of:
25 °C

Additional information

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