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Physical & Chemical properties

Water solubility

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water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
October 2017 - Maarch 2018
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
according to guideline
OECD Guideline 105 (Water Solubility)
according to guideline
EU Method A.6 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Type of method:
column elution method
Specific details on test material used for the study:
Identity: Triazolone
Appearance: Off-white powder
Storage conditions: Room temperature (15 to 25°C), dark
Batch number: 0727/16
Purity: 99%
Expiry date: 28 April 2019
Date received: 28 April 2017
Key result
Water solubility:
ca. 76 g/L
Conc. based on:
test mat.
Incubation duration:
ca. 3 d
20 °C
Details on results:
The detector calibration was found to be linear over the range 0 to 100 mg/L with a regression coefficient of 0.9997.
It shows a measured solubility of 75.9 ± 1.7 g/L.
An acceptable mean recovery of approximately 101% of Triazolone from fortified samples was achieved. Table 4 shows the recovery data.


The water solubility of Triazolone was determined to be 76g/L at 20°C.
Executive summary:

A study was performed to determine some physicochemical properties of the test item, Triazolone. The methods followed are amongst those described in Council Regulation (EC) No. 440/2008 and the OECD Guidelines for the Testing of Chemicals. The physicochemical properties which have been determined in this study are detailed below, together with the result obtained for each test.

The water solubility of Triazolone was determined to be 76 g/L at 20°C.

Description of key information

The water solubility of Triazolone was determined to be 76g/L at 20°C.

Key value for chemical safety assessment

Water solubility:
76 g/L
at the temperature of:
20 °C

Additional information