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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 201 (Freshwater Alga and Cyanobacteria, Growth Inhibition Test)
Version / remarks:
23 Mar 2006
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method C.3 (Algal Inhibition test)
Version / remarks:
07 Dec 2015
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: Guidance document on aquatic toxicity testing of difficult items and mixtures, OECD series on testing and assessment number 23
Version / remarks:
14 Dec 2000
Deviations:
no
GLP compliance:
yes

Test material

Constituent 1
Reference substance name:
3-[2-({[4-methanesulfonyl-2-(trifluoromethyl)phenyl]methyl}amino)pyridin-3-yl]prop-2-yn-1-ol
Cas Number:
2092997-91-4
Molecular formula:
not applicable
IUPAC Name:
3-[2-({[4-methanesulfonyl-2-(trifluoromethyl)phenyl]methyl}amino)pyridin-3-yl]prop-2-yn-1-ol

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
72 h

Results and discussion

Effect concentrationsopen allclose all
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
3 mg/L
Nominal / measured:
meas. (initial)
Conc. based on:
test mat.
Basis for effect:
growth rate
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
3 mg/L
Nominal / measured:
meas. (initial)
Conc. based on:
test mat.
Basis for effect:
other: yield
Duration:
72 h
Dose descriptor:
EC10
Effect conc.:
5.8 mg/L
Nominal / measured:
meas. (initial)
Conc. based on:
test mat.
Basis for effect:
growth rate
Remarks on result:
other:
Remarks:
95% confidence interval: 5.0 - 6.3 mg/L
Duration:
72 h
Dose descriptor:
EC10
Effect conc.:
4.4 mg/L
Nominal / measured:
meas. (initial)
Conc. based on:
test mat.
Basis for effect:
other: yield
Remarks on result:
other:
Remarks:
95% confidence interval: 3.9 - 4.7 mg/L
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
8.6 mg/L
Nominal / measured:
meas. (initial)
Conc. based on:
test mat.
Basis for effect:
growth rate
Remarks on result:
other:
Remarks:
95% confidence interval 8.3 - 9.0 mg/L
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
6 mg/L
Nominal / measured:
meas. (initial)
Conc. based on:
test mat.
Basis for effect:
other: yield
Remarks on result:
other:
Remarks:
95% confidence interval: 5.7 - 6.5 mg/L

Applicant's summary and conclusion