Registration Dossier
Registration Dossier
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EC number: 701-276-1 | CAS number: -
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
A 14d-EC50 of >1000 mg/kg soil (d.w.) was obtained for the test substance for the earthworm Eisenia fetida according to OECD 207.
No long-term terrestrial tests have been performed due to the hydrolytic instability of the test substance.
Key value for chemical safety assessment
- Short-term EC50 or LC50 for soil macroorganisms:
- 1 000 mg/kg soil dw
Additional information
The test substance is covered by the category approach of methylenediphenyl diisocyanates (MDI). Hence, data of the category substances can be used to cover this endpoint. A short-term toxicity study (van der Hoeven et al, 1992), carried out according to OECD 207, is available for PMDI for the earthworm Eisenia fetida. In this limit test, a 14d-EC50 of >1000 mg/kg soil (d.w.) was obtained in artificial soil. The endpoint was based on mortality, weight increase, behaviour and appearance.
No long-term terrestrial tests on soil macro-organisms are available for the test substance. Because MDI reacts readily with water to form predominantly insoluble and inert polyurea (Yakabe et al, 1994), long-term terrestrial toxicity tests are not appropriate for the derivation of PNEC values.
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