Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-920-4 | CAS number: 75-97-8
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 3,3-dimethylbutanone
- EC Number:
- 200-920-4
- EC Name:
- 3,3-dimethylbutanone
- Cas Number:
- 75-97-8
- Molecular formula:
- C6H12O
- IUPAC Name:
- 3,3-dimethylbutanone
- Test material form:
- liquid
1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 100 mg/L
- Based on:
- not specified
Parameter followed for biodegradation estimationopen allclose all
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Parameter followed for biodegradation estimation:
- O2 consumption
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
% Degradationopen allclose all
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 30.76
- Sampling time:
- 28 d
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 1.2
- Sampling time:
- 10 d
- Details on results:
- The degradation of the 10-day window failed (<60%).
The degradation rate of the test item Pinacolone reached at 30.76% after 28 days of incubation.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The biodegradation potential of Pinacolone was determined according to OECD 301F guideline. The study shows that the degradation rate of the test item Pinacolone reached at 30.76% after 28 days of incubation. Therefore, the test substance is not considered to be readly biodegradable.
- Executive summary:
The biodegradation potential of Pinacolone was determined according to OECD 301F guideline. The study shows that the degradation rate of the test item Pinacolone reached at 30.76% after 28 days of incubation. Therefore, the test substance is not considered to be readly biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
