Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
22 December 2017 - 07 June 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
2016
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Version / remarks:
1996
Deviations:
no
GLP compliance:
yes
Type of method:
effusion method: isothermal thermogravimetry

Test material

Constituent 1
Chemical structure
Reference substance name:
(1R,3aS,3bR,9aR,9bS,11aS)-1-ethynyl-1-hydroxy-11a-methyl-1H,2H,3H,3aH,3bH,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
EC Number:
608-630-3
Cas Number:
31528-46-8
Molecular formula:
C20H24O2
IUPAC Name:
(1R,3aS,3bR,9aR,9bS,11aS)-1-ethynyl-1-hydroxy-11a-methyl-1H,2H,3H,3aH,3bH,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
Test material form:
solid: particulate/powder
Details on test material:
Appearance: Off-white powder
Test item storage: At room temperature
Specific details on test material used for the study:
Decomposition temp.: > 275°C

Results and discussion

Vapour pressureopen allclose all
Key result
Temp.:
20 °C
Vapour pressure:
< 0 Pa
Key result
Temp.:
25 °C
Vapour pressure:
< 0 Pa

Any other information on results incl. tables

Results of the Vapour pressure Isothermal TGA Analysis

Temperature
[°C]

Weight loss
[µg/min]

νT
[g/cm2/h]

log νT

log PT

PT
[Pa]

170

1.47793

1.76x10-4

-3.75

0.33

2.2

 

1.38873

1.66x10-4

-3.78

0.30

2.0

180

2.73774

3.27x10-4

-3.49

0.68

4.7

 

2.60389

3.11x10-4

-3.51

0.65

4.4

190

5.65965

6.76x10-4

-3.17

1.08

12

 

5.38713

6.43x10-4

-3.19

1.05

11

200

12.1226

1.45x10-3

-2.84

1.50

32

 

11.1980

1.34x10-3

-2.87

1.46

29

Calculated Vapour Pressure of the Test Item

Temperature
[°C]

logPT

PT
[Pa]

PT
[mm Hg]

20

-9.14

7.2x10-10

5.0x10-12

25

-8.68

2.1x10-9

1.6x10-11

The calculated vapour pressure of the test item was outside the validated range of the method.

According to this, the vapour pressure of the test item was determined to be lower than that of benzo(ghi)perylene

Vapour Pressure of the Test Item

20°C

25°C

[Pa]

[mm Hg]

[Pa]

[mm Hg]

< 1.3x10-8

< 1.0x10-10

< 7.2x10-8

< 5.4x10-10

Applicant's summary and conclusion

Conclusions:
The vapour pressure of the substance at 20°C and 25°C was determined to be <1.3E-8 Pa and <7.2E-8 Pa, resp.
Executive summary:

The vapour pressure of the substance was determined using the isothermal thermogravimetric effusion method in a GLP study according to EC A.4, OECD 104 and OPPTS 830.7950.

A vapour pressure curve was constructed from 5 reference substances. As the calculated vapour pressure of the test item was outside the validated range of the method, the vapour pressure of the test item was determined to be lower than that of benzo(ghi)perylene.

The vapour pressure of the substance at 20°C and 25°C was concluded to be <1.3E-8 Pa and <7.2E-8 Pa, resp.